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Description:
Chemical Name: Fluocinolone (floo-oh-SIN-oh-lone) Fluocinolone has anti-inflammatory, antipruritic, and vasoconstrictive properties. The mechanism of the anti-inflammatory activity of the topical steroids, in general, is unclear. However, corticosteroids are thought to act by the induction of phospholipase A2 inhibitory proteins, collectively called lipocortins. It is postulated that these proteins control the biosynthesis of potent mediators of inflammation such as prostaglandins and leukotrienes by inhibiting the release of their common precursor arachidonic acid. Arachidonic acid is released from membrane phospholipids by phospholipase A2.
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Cautions:
SIDE EFFECTS that may occur while taking this medication includes dryness, itching, burning, local irritation, change in pigmentation and secondary infections.
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