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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Kisqali

Sezzle
Brand

Kisqali (Ribociclib)

Prescription Required

Strength
Qty
200mg
400mg
600mg

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  • Product Details

    Description

    Kisqali (ribociclib) is a medication used in combination with other drugs to treat breast cancer. It decreases the size of tumors by disrupting the replication cycle of the cancerous cells. You can buy Kisqali as a 200mg, 400mg, or 600mg tablet. Keep your Kisqali tablets stored at room temperature and out of reach of children.    

    Directions

    • You can take Kisqali with or without food.
    • Do not break or chew Kisqali. Swallow the tablets whole.
    • Take your Kisqali at the same time every day, preferably in the morning.   
    • Take your Kisqali precisely as your physician has prescribed.
    • If you miss a dose of Kisqali, continue with your next scheduled dose. Do not take any extra tablets to make up for a missed dose.
    • If you vomit after you take a Kisqali tablet, skip the dose and continue with your regular schedule. Do not take extra tablets to make up for doses that were vomited up.
    • The typical dose of Kisqali is 600mg once daily for 21 days, followed by seven days without treatment.

    Ingredients

    The active ingredient in Kisqali is ribociclib. For a full list of inactive ingredients, see the package insert.


    Fact Table

    Formula

    C23H30N8O

    License

    US FDA

    Bioavailability

    -

    Legal status

    RX Only

    Chemical Name

    Ribociclib

    Elimination half-life

    29.7-54.7 hours

    Dosage (Strength)

    200mg (21 Tablets), 400mg (42 Tablets), 600mg (42 Tablets)

    Pregnancy

    Consult a doctor

    Brands

    Kisqali

    Protein binding

    70%

    PubChem CID

    44631912

    MedlinePlus

    a617008

    ChEBI

    -

    ATC code

    L01EF02

    DrugBank

    DB11730

    KEGG

    D10883

    Routes of administration

    By mouth (tablets)

    Cautions

    • Kisqali can affect your blood cells, liver, and heart. Talk to your doctor about your risks.
    • Do not take Kisqali tablets that are cracked or broken.
    • Do not take Kisqali if you have a known allergy to ribociclib or any other ingredient listed in the package insert.
    • If you have any episodes of fainting or seizures while taking Kisqali, contact your doctor or seek emergency assistance immediately. These symptoms could mean you have a dangerous heart condition.
    • Kisqali can cause lung problems. If you experience difficulty breathing while using Kisqali, contact your doctor.
    • Do not take Kisqali if you are pregnant. Talk to your doctor about the risks of using Kisqali during pregnancy.
    • Avoid grapefruit and grapefruit juice while taking Kisqali.
    • Discuss any medications you take with your physician to avoid serious drug interactions with Kisqali.

    Side Effects

    Common Kisqali side effects can include:

    • Hair loss
    • Itching
    • Constipation
    • Diarrhea
    • Nausea
    • Vomiting
    • Leukopenia
    • Neutropenia
    • Infectious disease
    • Joint pain
    • Back pain
    • Headache
    • Cough
    • Fatigue

    Serious side effects of Kisqali can include:

    • Prolonged QT interval
    • Sudden cardiac death
    • Fainting
    • Anemia
    • Febrile neutropenia
    • High-grade leukopenia
    • Lymphocytopenia
    • High-grade neutropenia
    • Interstitial lung disease
    • Pneumonitis

    Other Considerations

    Compare the Kisqali cost at Canada Pharmacy to your local drug store.

    References:

    1. Kisqali. (n.d.). Retrieved March 23, 2020
    2. DailyMed - kisqali- RIBOCICLIB TABLET, film coated. (2020). Retrieved March 23, 2020 

    Frequently Asked Questions about Kisqali (Ribociclib)

    What is Kisqali (Ribociclib)?

    Kisqali (ribociclib) is a prescription medication used in combination with other drugs to treat certain types of breast cancer.

    How does Kisqali work?

    Kisqali is a type of drug known as a CDK4/6 inhibitor. It works by interfering with the cancer cell cycle, preventing the cells from dividing and growing.

    Who can take Kisqali?

    Kisqali is prescribed to postmenopausal women and men with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced or metastatic breast cancer.

    How is Kisqali taken?

    Kisqali is taken orally, usually once a day, in combination with another medication. It's important to follow your doctor's instructions on how to take it.

    What are the common side effects of Kisqali?

    Some common side effects include nausea, fatigue, hair loss, vomiting, and diarrhea. Always consult with your healthcare provider about potential side effects.

    Can I take Kisqali while pregnant or breastfeeding?

    No, Kisqali can harm an unborn baby. It's important to use effective contraception while on this medication and for some time after the last dose. It's also recommended not to breastfeed while taking Kisqali and for a specific period after the last dose.

    How should I store Kisqali?

    Store Kisqali at room temperature, away from moisture and heat. Keep it out of reach of children.

    What should I do if I miss a dose?

    If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once.

    Can I drink alcohol while taking Kisqali?

    It's best to discuss this with your healthcare provider. Alcohol may interact with Kisqali or exacerbate some of its side effects.

    Are there any drugs that interact with Kisqali?

    Yes, several drugs can interact with Kisqali. It's crucial to inform your doctor about all medications, supplements, and herbal products you are taking.

    Product Code : 13252

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