What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Steglatro (Ertugliflozin)
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Product Details
Description
Steglatro is used with diet and exercise to help control blood sugar levels in adults with type 2 diabetes. Steglatro is classified as a sodium glucose co-transporter 2 (SGLT2) inhibitor.
The generic name for Steglatro is Ertugliflozin.
Fact Table
Formula
C22H25ClO7
License
US DailyMed
Bioavailability
~100%
Legal status
Rx-only
Chemical Name
Ertugliflozin
Elimination half-life
~17 hours
Dosage (Strength)
5mg, 15mg
Pregnancy
Consult Doctor
Brands
Steglatro
Protein binding
93.6%
PubChem CID
44814423
MedlinePlus
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ChEBI
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ATC code
A10BK04
DrugBank
DB11827
KEGG
D10313
Routes of administration
By mouth
Directions
Steglatro is supplied as either 5 mg or 15 mg tablets. The dosage ranges from 5 mg to 15 mg by mouth once daily in the morning with or without food.
It's important to evaluate the health of your kidneys before starting Steglatro use.
Ingredients
The active ingredient in Steglatro is Ertugliflozin.
Contraindications
You should discuss your allergies with your doctor. Do not take Steglatro if you are allergic to ertugliflozin or any of the other ingredients in Steglatro.
Do not take Steglatro if you are on dialysis.
Cautions
Once you are prescribed and buy Steglatro, know that there are certain medications that may interact with Steglatro. Before you start taking Steglatro, tell your doctor about any vitamins, herbal supplements, prescription, and over-the-counter medications you take.
- Stop taking Steglatro and call your doctor if you experience symptoms of ketoacidosis, including abdominal pain, nausea, vomiting, fatigue, and breathing problems.
- Stelagtro may increase your risk for leg or foot amputation. Immediately call your doctor if you experience new pain, tenderness, sores, infections, or ulcers in your lower limbs. Your doctor may then stop your Stelagtro.
- Before starting Steglatro, your kidney function should be evaluated and volume status corrected. Immediately tell your doctor if you are unable to eat or drink regularly or if you have nausea, vomiting, diarrhea, or have been in the heat too long because you could be dehydrated. Dehydration can cause kidney damage.
- If you are taking Steglatro with other medications that can lower your blood sugar, your blood sugar levels can drop. Use caution and monitor for symptoms of low blood sugar such as hunger, headache, irritability, shakiness, sweating, confusion, weakness, or a fast heartbeat. You should treat your low blood sugar as your doctor has instructed.
- You should seek medical care right away if you develop a fever or feel fatigued, weak, and have pain, swelling, or redness around your anus and genitals. These could be signs of a rare but serious bacterial infection that can damage the tissues beneath the skin near your anus and genitals.
- Consult your doctor if you have odor or white to yellowish discharge coming from your vagina or if you have vaginal itching. These could be signs that you have a vaginal yeast infection.
- Consult your doctor if you have pain, redness, itching, or swelling of your penis or if you have an odorous discharge that is coming from your penis. These could be signs that you have a penile yeast infection.
- Tell your doctor if you experience changes in urination, have pain or burning when urinating or if your urine is cloudy, light-pink, or red as these can be signs that you have a urinary tract infection.
- Tell your doctor if you are pregnant or plan to become pregnant. Because there is potential risk to the fetus, you should avoid taking Steglatro during the second and third trimesters of pregnancy.
- Tell your doctor if you are breastfeeding or plan to breastfeed. You should avoid taking Steglatro if you are breastfeeding.
Side Effects
If you experience any adverse effects while taking Steglatro, be sure to tell your doctor. Common side effects include:
- Changes in urination
- Vaginal yeast infection
- Penile yeast infection
References:
- STEGLATRO Prescribing Information. Whitehouse Station, NJ: Merk Sharp & Dhome Corp., 2021.
- Steglatro (ertugliflozin). Accessed November 9, 2021.
- Urinary tract infection (UTI). Mayo Clinic. Accessed November 16, 2021.
Frequently Asked Questions about Steglatro
What is Steglatro?
Steglatro is an oral medication for type 2 diabetes. It controls blood sugar levels by helping the kidneys eliminate glucose from the bloodstream.
Who should not use Steglatro?
Do not use Steglatro if you have severe kidney disease, are on dialysis, or are allergic to ertugliflozin. It's also not recommended for those with a history of leg amputation, foot ulcers, heart disease, circulation or nerve problems, liver or kidney disease, bladder infections, low blood pressure, diabetic ketoacidosis, pancreas problems, or if on a low salt diet.
How should Steglatro be taken?
Steglatro is generally taken once a day in the morning, with or without food. Dosage may be adjusted by your doctor. It's important to maintain regular blood sugar monitoring.
What are the symptoms of hypoglycemia and hyperglycemia while taking Steglatro?
Symptoms of low blood sugar (hypoglycemia) include headache, hunger, sweating, irritability, dizziness, nausea, and fast heart rate. Symptoms of high blood sugar (hyperglycemia) include increased thirst or urination, blurred vision, headache, and tiredness.
What is the usual dosage for Steglatro?
The initial dose is typically 5 mg once daily, which may be increased to 15 mg for additional glycemic control.
What should I do if I miss a dose or overdose?
If you miss a dose, take it as soon as possible unless it's almost time for your next dose. In case of overdose, seek emergency medical attention.
Are there any special precautions to take when using Steglatro?
Avoid getting up too fast from a sitting or lying position to prevent dizziness. Also, inform your doctor or dentist that you are using this medication, especially before surgery or medical tests.
What are the side effects of Steglatro?
Common side effects include genital infections, increased urination, and symptoms of urinary tract infections. Serious side effects can include ketoacidosis, severe dehydration, kidney problems, and lower leg or toe amputation. There's a risk of a rare bacterial infection known as Fournier's gangrene.
How does Steglatro interact with other medications?
Steglatro may interact with other diabetes medications, requiring dose adjustments. Inform your doctor about all medications, vitamins, and herbal supplements you are taking.
Is Steglatro safe for use in children, the elderly, during pregnancy, or while breastfeeding?
The safety and efficacy of Steglatro in children have not been established. While no geriatric-specific problems have been observed, elderly patients with kidney issues should use it cautiously. Steglatro is not recommended during the second or third trimester of pregnancy and should not be used while breastfeeding.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13235
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