Humalog 75/25 (Insulin Lispro)

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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details


    HUMALOG mix 75/25 is a prescription medication used to treat diabetes mellitus. It can be used for the treatment of either type 1 diabetes mellitus or type 2 diabetes mellitus.

    People with diabetes have blood sugar that is too high. Insulin helps to lower and correct blood sugar to normal levels.


    The dose of insulin HUMALOG 75/25 is dosed based on the individual. Take it exactly as prescribed by your doctor.

    Your doctor may have you take a set dose every day or may have you adjust your dose based on your blood sugar levels.


    HUMALOG 75/25 contains a mixture of a rapid-acting insulin and intermediate-acting insulin.

    Insulin lispro is a rapid-acting insulin that begins working in about 15 minutes. While taking rapid-acting insulin products, it is essential not to skip meals, or you may experience low blood sugar.

    Insulin lispro protamine suspension is an intermediate-acting insulin. It begins working in about 1 hour and lasts for 12 hours. This insulin makes up 75% of HUMALOG 75/25. This insulin mixture provides around-the-clock coverage for high blood sugar.


    Insulin has drug interactions that are different from other types of drugs. There are no direct drug-drug interactions, but certain medications can change the levels of blood sugar. Common drugs that impact blood sugar include:

    • Blood pressure medications
    • Corticosteroids
    • Estrogens
    • Isoniazid
    • Mono-amine oxidase inhibitors (MAOIs)
    • Niacin
    • Oral antidiabetic agents
    • Oral contraceptives
    • Phenothiazines
    • Salicylates
    • Sulfa antibiotics
    • Thyroid replacement medication

    Tell your doctor or pharmacist if you are taking any of the above medications. Your dose of insulin may need to be adjusted.


    Use caution if you have a history of kidney or liver problems. These conditions will affect the dose of insulin required for diabetes treatment.

    Insulin increases the risk of hypoglycemia, which is when the blood sugar is too low. Ask your doctor or pharmacist if you are not familiar with the symptoms. Some symptoms of hypoglycemia may include:

    • Anxiety
    • Confusion
    • Dizziness
    • Fatigue
    • Hunger
    • Irritability
    • Pale skin
    • Sweating
    • Tremor

    Low blood sugar can be a medical emergency. Speak with your doctor about how you should manage these symptoms.

    Side Effects

    Side Effects

    The most common side effects of insulin products are:

    • Allergic reactions
    • Hypoglycemia
    • Injection site reactions
    • Lipodystrophy
    • Pruritis
    • Rash


    1. Humalog 75/25 [package insert].Indianapolis, IN: Lilly; 2007.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13355

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