Humulin N (Insulin)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    HUMULIN N is a prescription medication that can treat hyperglycemia (high blood sugar) in people diagnosed with diabetes. 

    HUMULIN N is available as either a vial or pen. 

    The vial requires a separate needle and syringe for injection. HUMULIN N insulin pen is a convenient option that does not require drawing up the medication. HUMULIN N pens are prefilled with insulin and can be adjusted to inject pre-set amounts.

    Directions

    Administer HUMULIN N vial or HUMULIN N pen subcutaneously (under the skin) as directed by your prescribing physician. The dose of insulin is unique and should not be adjusted unless directed.

    Store HUMULIN N in the refrigerator before opening (36° to 46°F [2° to 8°C]). Once opened, the package can be stored at room temperature for 28 days and then discarded.

    Ingredients

    The active ingredient in HUMULIN N is human insulin isophane or NPH insulin. NPH insulin is an intermediate-acting insulin.

    NPH insulin can last between 12 to 16 hours. Two injections per day are often enough for around-the-clock coverage. However, additionally, mealtime insulin may be required for proper blood glucose control.

    Interactions

    The following can affect blood sugar, requiring higher or lower doses of insulin:

    • Alcohol
    • Atypical Antipsychotics
    • Beta-blockers
    • Clonidine
    • Corticosteroids
    • Disopyramide
    • Diuretics
    • Estrogens/Progesterones
    • Fibrates
    • Fluoxetine
    • Isoniazid
    • Lithium
    • Monoamine Oxidase Inhibitors (MAOIs)
    • Niacin
    • Oral antidiabetic agents
    • Pentoxifylline
    • Phenothiazine derivatives
    • Pramlintide
    • Propoxyphene
    • Protease inhibitors
    • Salicylates
    • Somatostatin Analogues
    • Somatropin
    • Sulfonamide Antibiotics
    • Sympathomimetic agents
    • Thyroid replacement medication

    Cautions

    Never share insulin pens between patients, even if the pen needle is changed.

    Insulin treatment increases the risk of hypoglycemia (low blood sugar), which may be life-threatening.

    Tell your doctor if you have a history of hypokalemia (low potassium), liver dysfunction, or kidney dysfunction.

    Side Effects

    The most common side effects of HUMULIN N can include:

    • Allergic reactions
    • Edema
    • Hypoglycemia
    • Injection site reactions
    • Lipodystrophy
    • Pruritis
    • Rash
    • Weight gain

    References

    Humulin N [package insert].Indianapolis, IN: Lilly; 2019.

    Product Code : 13359

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