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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Vraylar (Cariprazine)
Also Known as Reagila
Prescription Required
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Product Details
Description
Vraylar is a prescription drug used to treat schizophrenia and bipolar disorder. Vraylar is effective at treating thought and mood disorders. It works by modulating the effects of dopamine in the brain.
Fact Table
Formula
C21H32Cl2N4O
License
US FDA
Bioavailability
High
Legal status
Rx-only
Chemical Name
Cariprazine
Elimination half-life
2–5 days
Dosage (Strength)
1.5mg, 3mg, 4.5mg, 6mg
Pregnancy
Consult Doctor
Brands
Vraylar, Reagila
Protein binding
91–97%
PubChem CID
11154555
MedlinePlus
a615050
ChEBI
90933
ATC code
N05AX15
DrugBank
DB06016
KEGG
D09997
Routes of administration
By mouth
Directions
The usual starting dose of Vraylar is 1.5 mg once daily.
Your doctor may increase your dose to 1.5-6 mg once daily, depending on the condition being treated.
Take Vraylar exactly as prescribed by your doctor.
Ingredients
The active ingredient in Vraylar is cariprazine.
Interactions
Vraylar has many potential drug-drug interactions, including:
- Amiodarone
- Apalutamide
- Aprepitant
- Atazanavir
- Berotralstat
- Bexarotene
- Bosentan
- Carbamazepine
- Cenobamate
- Ceritinib
- Cimetidine
- Clarithromycin
- Conivaptan
- Crizotinib
- Cyclosporine
- Dabrafenib
- Darunavir
- Dexamethasone
- Diltiazem
- Dipyrone
- Dronedarone
- Duvelisib
- Efavirenz
- Enzalutamide
- Erythromycin
- Eslicarbazepine
- Etravirine
- Fedratinib
- Fluconazole
- Fosamprenavir
- Fosaprepitant
- Fosphenytoin
- Grapefruit juice
- Idelalisib
- Imatinib
- Indinavir
- Itraconazole
- Ketoconazole
- Lefamulin
- Letermovir
- Lonafarnib
- Lopinavir
- Lorlatinib
- Lumacaftor
- Lumacaftor-ivacaftor
- Mifepristone
- Mitotane
- Modafinil
- Nafcillin
- Nefazodone
- Nelfinavir
- Netupitant
- Nilotinib
- Pexidartinib
- Phenobarbital
- Phenytoin
- Posaconazole
- Primidone
- Ribociclib
- Rifabutin
- Rifampin (rifampicin)
- Rifapentine
- Saquinavir
- Schisandra
- St. John's wort
- Telithromycin
- Tucatinib
- Verapamil
- Voriconazole
Cautions
Vraylar and other antipsychotic medications should not be used to treat dementia-related psychosis in older adults.
Tell your doctor if you experience suicidal thoughts or behaviors while taking Vraylar.
Tell your doctor if you have a history of kidney or liver problems.
Use with caution if you have a history of seizure disorders.
Side Effects
The most common side effects with Vraylar may include:
- Abdominal pain
- Akathisia
- Anxiety
- Arthralgia
- Suicidal ideation
- Back pain
- Blurred vision
- Constipation
- Decreased appetite
- Diarrhea
- Dizziness
- Drowsiness
- Dyspepsia
- Dystonia
- Extrapyramidal reactions
- Fatigue
- Headache
- Hypertension
- Increased creatinine phosphokinase
- Increased liver enzymes
- Insomnia
- Agitation
- Limb pain
- Muscle rigidity
- Nausea
- Parkinsonian-like syndrome
- Restlessness
- tachycardia
- Toothache
- Vomiting
- Weight gain
- Xerostomia
References
Vraylar [package insert]. Parsippany, NJ: Actavis; 2015.
Frequently Asked Questions about Vraylar (Cariprazine)
What is Vraylar (Cariprazine)?
Vraylar, also known as Cariprazine, is a prescription medication used to treat various mental health conditions, including schizophrenia and bipolar disorder.
How does Vraylar work?
Vraylar works by acting on certain receptors in the brain, helping to regulate the balance of chemicals such as dopamine and serotonin. This can help manage the symptoms of schizophrenia and bipolar disorder.
What conditions does Vraylar treat?
Vraylar is primarily used to treat schizophrenia in adults and bipolar disorder in adults and children aged 10-17 years. It may also be prescribed for other mental health conditions as determined by a healthcare provider.
Is Vraylar safe for children and adolescents?
Vraylar may be prescribed to children and adolescents aged 10-17 years for the treatment of bipolar disorder, but its safety and effectiveness should be discussed with a healthcare provider.
What are the common side effects of Vraylar?
Common side effects of Vraylar may include drowsiness, restlessness, weight gain, and abnormal movements. It's important to report any side effects to your healthcare provider.
How long does it take for Vraylar to start working?
The time it takes for Vraylar to take effect can vary from person to person. Some individuals may experience an improvement in symptoms within a few weeks, while others may take longer.
Is it safe to drink alcohol while taking Vraylar?
It's generally recommended to avoid alcohol while taking Vraylar, as it may increase the risk of side effects and interactions. Consult your healthcare provider for specific guidance.
Can Vraylar be taken during pregnancy or while breastfeeding?
Vraylar's safety during pregnancy and breastfeeding is not well-established. It's essential to discuss the risks and benefits with your healthcare provider if you are pregnant, planning to become pregnant, or breastfeeding.
Can Vraylar cause withdrawal symptoms if I stop taking it?
Stopping Vraylar abruptly can lead to withdrawal symptoms. It is essential to follow your healthcare provider's guidance when discontinuing the medication to minimize the risk of withdrawal effects.
Are there any lifestyle changes I should make while taking Vraylar?
It is essential to maintain a healthy lifestyle while taking Vraylar. This includes regular exercise, a balanced diet, and managing stress. Additionally, attend follow-up appointments with your healthcare provider for monitoring and adjustments as needed.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13344
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