What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Ampyra (dalfampridine er)
Also Known as Fampyra
Prescription Required
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Product Details
Description
Amprya is an oral medication prescribed for patients with Multiple Sclerosis (MS).
MS is a disease that affects several different systems in the body. MS is an autoimmune disease where the immune system incorrectly attacks parts of the body. In MS, the immune system attacks the myelin sheaths that protect nerve cells.
The breakdown of myelin sheaths affects the connections between the brain and several parts of the body, including the eyes, the limbs, and sexual organs. It can cause fatigue, cognitive problems, pain, and other symptoms.
Fact Table
Formula
C5H6N2
License
US FDA, EU EMA
Bioavailability
96%
Legal status
Rx-Only
Chemical Name
Dalfampridine
Elimination half-life
125 +/- 23 min
Dosage (Strength)
10mg
Pregnancy
Consult Doctor
Brands
Ampyra
Protein binding
3–7%
PubChem CID
1727
MedlinePlus
a611005
ChEBI
34345
ATC code
N07XX07
DrugBank
DB06637
KEGG
D04127
Routes of administration
Oral
Directions
The standard and maximum doses are 10 mg by mouth every 12 hours.
Amprya may be taken with or without food. The capsules should not be crushed, chewed, and opened.
If you miss a dose, do not take double the amount. Call your pharmacist for directions on what to do.
Ingredients
The active ingredient in Ampyra generic is dalfampridine.
Interactions
Common drug-drug interactions that can occur with Ampyra may include:
- Cimetidine
- Doxepin
- Dolutegravir
- Metformin
- Pantoprazole
- Quinidine
- Trilaciclib
- Trospium
Talk with your pharmacist and doctor about all the medications you are currently taking.
Cautions
Tell your doctor if you have a history of seizures. If you have a seizure while taking this medication, it should be discontinued.
If you experience an allergic reaction while taking this medication, it should be stopped and not restarted.
Ampyra should not be taken by women who are pregnant or trying to become pregnant.
Older adults should have their kidney function checked before starting this medication.
Side Effects
Common Ampyra side effects may include:
- Acute exacerbations of multiple sclerosis
- Anaphylaxis
- Angioedema
- Asthenia
- Back pain
- Balance impairment
- Confusion
- Constipation
- Dizziness
- Dyspepsia
- Headache
- Insomnia
- Nasopharyngitis
- Nausea
- Paresthesia
- Pharyngolarygeal pain
- Seizure
- Urinary tract infection
- Vertigo
- Vomiting
References
Ampyra [package insert]. Ardsley, NY: Acorda; 2021.
Frequently Asked Questions about Ampyra (Dalfampridine)
What is Ampyra used for?
Ampyra (dalfampridine) is prescribed to improve walking in adults with multiple sclerosis (MS).
How does Ampyra work?
Ampyra improves nerve function by blocking potassium channels, aiding in better conduction of nerve signals.
What is the recommended dosage of Ampyra?
The typical dosage is 10 mg twice daily, approximately 12 hours apart.
How soon can I expect to see results with Ampyra?
Improvement in walking speed is usually noticed within 2-4 weeks of starting Ampyra.
Are there any common side effects of Ampyra?
Common side effects include insomnia, dizziness, and urinary tract infections.
Can Ampyra be used with other MS medications?
Ampyra can be used with other MS medications, but it's important to consult your doctor for personalized advice.
Is Ampyra suitable for all types of multiple sclerosis?
Ampyra is indicated for adults with all types of MS, but its effectiveness may vary.
What should I do if I miss a dose of Ampyra?
If you miss a dose, skip it and take your next dose at the scheduled time. Do not double the dose to make up for a missed one.
Can pregnant or breastfeeding women use Ampyra?
The safety of Ampyra in pregnant or breastfeeding women is not well-established, so consult your healthcare provider before use.
Is Ampyra a cure for multiple sclerosis?
No, Ampyra is not a cure for MS. It is a symptomatic treatment designed to improve walking ability in individuals with MS.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13258
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