What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Breo Ellipta (Fluticasone Furoate & Vilanterol Trifenatate)

Also Known as Relvar Ellipta

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Brand

Breo Ellipta (Fluticasone Furoate & Vilanterol Trifenatate)

Prescription Required

Strength
Qty
184 / 22mcg(200 / 25mcg) (30 doses / inhaler)
92 / 22mcg(100 / 25mcg) (30 doses / inhaler)
100 / 25mcg (14 puffs / 28 blisters / inhaler)
100 / 25mcg (30 puffs / 60 blisters / inhaler)

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  • Product Details

    Description

    BREO ELLIPTA (Umeclidinium) is a prescription that contains a combination of medications and is prescribed to treat asthma and chronic obstructive pulmonary disease (COPD). Asthma and COPD are diseases of the lungs that make it difficult for a person to breathe. BREO ELLIPTA is a daily medication that helps to reduce some of the symptoms like shortness of breath, coughing, and wheezing.

    Directions

    The usual dosage is one inhalation once daily when using BREO ELLIPTA for cough and the reduction of other symptoms.

    After inhalation, rinse the mouth with water and do not swallow. If the mouth is not rinsed after use, the risk of oropharyngeal candidiasis (oral thrush) may increase.

    BREO ELLIPTA should be taken every day. It is not a rescue medication and should not be used for the relief of acute bronchospasm. In the case of acute symptoms like shortness of breath, an inhaled medication like albuterol should be used for relief instead of a maintenance inhaler like BREO ELLIPTA.

    If used regularly, BREO ELLIPTA will reduce the severity of asthma and COPD symptoms and reduce the need for a rescue inhaler.

    Fact Table

    Formula

    C51H62Cl2F3NO11S

    License

    EU EMA

    Bioavailability

    15.2%

    Legal status

    US: RX Only

    Chemical Name

    Fluticasone Furoate & Vilanterol Trifenatate

    Elimination half-life

    24 hours

    Dosage (Strength)

    184/22mcg(200/25mcg) (30 doses/inhaler), 92/22mcg(100/25mcg) (30 doses/inhaler)30 days 100-25mcg 30 (1 inhaler), INST 14days 100-25mcg 28 (1 inhaler)

    Pregnancy

    Consult a doctor

    Brands

    Breo Ellipta

    Protein binding

    93%

    PubChem CID

    71306415

    MedlinePlus

    a603017

    ChEBI

    75043

    ATC code

    R03AK10

    DrugBank

    DB08906, DB09082

    KEGG

    D10501

    Routes of administration

    Inhaled

    Ingredients

    Fluticasone furoate

    Fluticasone is an inhaled corticosteroid medication (ICS). Corticosteroids are signaling molecules that reduce inflammation. During bronchospasms, the airways of the lungs are often swollen and inflamed, and regular usage of an ICS decreases this.

    Vilanterol

    Vilanterol is a long-acting beta2-agonist (LABA). Beta receptors are present on the surface of muscle cells in the lungs. By activating these receptors, vilanterol relaxes the muscles of the airway, making it easier to breathe.

    Cautions

    Breo Ellipta reducing exacerbations

    The usage of BREO ELLIPTA may increase the risk of pneumonia and other bronchial infections in certain patients.

    BREO ELLIPTA may rarely cause a paradoxical reaction where the airways spasm, making it harder to breathe. If this happens while taking BREO ELLIPTA, stop the medication and tell your physician.

    BREO ELLIPTA should be used with caution in patients with a history of cardiovascular disorders.

    BREO ELLIPTA should be used with caution in diabetic patients or those with a history of hypokalemia.

    Speak with your physician for a full list of warnings and precautions.

    Side Effects

    Common adverse effects of BREO ELLIPTA include:

    • Arthralgia
    • Back pain
    • Bronchitis
    • Cough
    • Dysphonia
    • Headache
    • Hypertension
    • Influenza
    • Nasopharyngitis
    • Oral candidiasis
    • Oropharyngeal pain
    • Pharyngitis
    • Pneumonia
    • Pyrexia
    • Sinusitis
    • Upper respiratory tract infection

    References


    Frequently Asked Questions about Breo Ellipta


    What is Breo Ellipta used for?

    Breo Ellipta is a prescription drug used to treat chronic obstructive pulmonary disorder (COPD) and asthma in adults. It’s not meant to be used as a rescue inhaler for sudden breathing problems.


    How to use Breo Ellipta?

    Breo Ellipta should be used once daily. To use Breo Ellipta daily, open the inhaler, exhale, inhale deeply through the mouthpiece, hold your breath for a few seconds, then cover the mouthpiece and store the inhaler.


    Is Breo Ellipta a steroid?

    Yes, Breo Ellipta contains fluticasone furoate, which is a corticosteroid.


    What is in Breo Ellipta?

    Breo Ellipta contains two active ingredients: fluticasone furoate, a corticosteroid, and vilanterol, a long-acting beta-agonist.


    How long can you stay on Breo?

    Breo Ellipta is meant to be a long-term treatment. If you and your doctor determine that Breo Ellipta is safe and effective for you, you’ll likely take it long term.


    What is the best time of day to take Breo Ellipta?

    Breo Ellipta should be used at the same time each day.


    Does Breo improve lung function?

    Yes, Breo Ellipta helps patients breathe better by improving lung function for a full 24 hours.


    Does Breo help with coughing?

    Yes, as part of your asthma maintenance plan, Breo Ellipta can prevent symptoms such as wheezing, coughing, chest tightness, and shortness of breath, and can help keep them from coming back.


    Can Breo cause weight gain?

    No, Breo Ellipta isn’t known to cause weight gain.


    How many puffs of Breo can you take a day?

    The maximum dosage of Breo Ellipta for asthma is one puff of the 200 mcg /25 mcg dose once per day.


    Why is Breo so expensive?

    The cost of Breo Ellipta can vary depending on your insurance coverage, the pharmacy you use, and your location. It’s a brand-name medication, which is often more expensive than their generic counterparts. As of now, there is no generic version of Breo Ellipta available.


    What happens if you suddenly stop taking Breo?

    Suddenly stopping Breo Ellipta may lead to withdrawal symptoms and worsening of your COPD or asthma symptoms. Always consult with your healthcare provider before making any changes to your medication regimen.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13156

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