What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Cardizem (Diltiazem)

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Generic Equivalent - Cardizem (Diltiazem)

Prescription Required

Strength
Qty
30mg
60mg
90mg
120mg

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  • Product Details

    Description

    Cardizem (diltiazem hydrochloride) is a medication used to manage chronic stable chest pain and chest pain due to coronary artery spasm.


    Fact Table

    Formula

    C22H26N2O4S

    License

    US DailyMed

    Bioavailability

    40%

    Legal status

    Rx-Only

    Chemical Name

    Diltiazem

    Elimination half-life

    3–4.5 hours

    Dosage (Strength)

    30mg, 60mg, 90mg, 120mg

    Pregnancy

    Not recommended

    Brands

    Cardizem

    Protein binding

    70-80%

    PubChem CID

    39186

    MedlinePlus

    a684027

    ChEBI

    101278

    ATC code

    C05AE03

    DrugBank

    DB00343

    KEGG

    D07845

    Routes of administration

    By mouth

    Directions

    The instructions that come with your Cardizem prescription should be carefully read and followed. If you have any questions or concerns, talk to your doctor or pharmacist.

    Cardizem is available in 30 mg, 60 mg, 90 mg, and 120 mg tablets that should not be crushed or chewed; they should be swallowed whole.

    The typical starting dose is 30 mg by mouth four times a day, before meals and at bedtime. 

    The dosage may be adjusted depending on how well you tolerate the medication. 

    Ingredients

    Each Cardizem tablet contains diltiazem, a calcium ion cellular influx inhibitor. 

    Contraindications

    Do not take Cardizem if you have sick sinus syndrome unless you have a functioning ventricular pacemaker.

    Do not take Cardizem if you have a second- or third-degree AV block unless you have a functioning ventricular pacemaker.

    Do not take Cardizem if you have a systolic blood pressure that is less than 90 mm HG. 

    Do not take Cardizem if you are allergic to diltiazem or any of its other ingredients.

    Do not take Cardizem if you have a heart attack and pulmonary congestion documented on X-ray when admitted to the hospital.

    Cautions

    • Before you start taking Cardizem, inform your doctor of:
      • All the medications you take, including all prescription and over-the-counter medications, herbal supplements, and vitamins
      • Your allergies
      • Your health conditions and medical history
      • Your pregnancy or breastfeeding status
    • Taking Cardizem with beta-blockers or digitalis may affect cardiac conduction. Ask your doctor if you are unsure whether or not you take beta-blockers or digitalis.
    • There is limited experience regarding the use of Cardizem by itself or with beta-blockers in patients who have impaired ventricular function. 
    • Cardizem can cause symptomatic low blood pressure.
    • Cardizem can cause sudden liver damage, although rare and reversible when Cardizem is stopped.

    Side Effects

    Cardizem (diltiazem) side effects include swelling, headache, nausea, dizziness, rash, and lack of energy; however, these may not be all the possible side effects of Cardizem. It's recommended to contact your doctor right away if you develop side effects that bother you or will not resolve.

    Reference:

    Cardizem (diltiazem hydrochloride). Bridgewater, NJ: Valeant Pharmaceuticals North America LLC; 2014.


    Frequently Asked Questions about Cardizem (Diltiazem)


    What is Cardizem (Diltiazem)?

    Cardizem, also known by its generic name Diltiazem, is a medication used to treat various heart and blood pressure conditions. It belongs to a class of drugs known as calcium channel blockers.


    What is Cardizem used for?

    Cardizem is prescribed to treat conditions such as hypertension (high blood pressure), angina (chest pain), and certain heart rhythm disorders, including atrial fibrillation and atrial flutter.


    How does Cardizem work?

    Cardizem works by relaxing blood vessels and reducing the workload on the heart. It does this by blocking the entry of calcium into the muscle cells of the heart and blood vessels, leading to a decrease in heart rate and blood pressure.


    What are the different forms of Cardizem available?

    Cardizem is available in various forms, including immediate-release tablets, extended-release capsules, and intravenous (IV) formulations.


    How should I take Cardizem?

    Follow your healthcare provider's instructions carefully. Generally, Cardizem is taken orally with or without food. It's important to take it at the same time each day for the best results.


    What should I do if I miss a dose of Cardizem?

    If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and resume your regular dosing schedule. Do not double up on doses.


    Are there any potential side effects of Cardizem?

    Yes, like all medications, Cardizem can cause side effects. Common side effects may include dizziness, headache, constipation, and flushing. Serious side effects are rare but can include slow heart rate, low blood pressure, and allergic reactions. Contact your doctor if you experience any unusual or severe side effects.


    Can I take other medications along with Cardizem?

    Cardizem may interact with other medications, including certain antibiotics, antifungals, and medications for high blood pressure. Always inform your healthcare provider about all the medications and supplements you are taking to avoid potential interactions.


    Can Cardizem cure my heart condition?

    Cardizem can help manage and control heart and blood pressure conditions, but it is not a cure. It is important to continue taking the medication as prescribed by your healthcare provider and follow their recommendations for a healthy lifestyle.


    How should I store Cardizem?

    Store Cardizem at room temperature, away from moisture and light. Keep it out of reach of children and pets.




    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 10082

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