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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Orgovyx (Relugolix)

Brand

Orgovyx (Relugolix)

Prescription Required

Strength
Qty
120mg

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  • Product Details

    Description

    Orgovyx (Relugolix) is a prescription medication used to treat adults with advanced prostate cancer. This medication lowers the production of two key hormones by blocking gonadotropin-releasing hormone (GnRH) receptors in the pituitary gland: Luteinizing hormone and follicle-stimulating hormone. This results in significantly reduced testosterone production, which helps slow the growth of cancer cells and controls the disease.

    Fact Table

    Formula

    C29H27F2N7O5S

    License

    US FDA, EMA

    Bioavailability

    Approximately 12%

    Legal status

    Rx-only

    Chemical Name

    Relugolix

    Elimination half-life

    25 hours effective; 60.8 hours terminal

    Dosage (Strength)

    120 mg tablets; 360 mg loading dose, then 120 mg once daily

    Pregnancy

    May cause fetal harm; not indicated for use in females

    Brands

    Orgovyx, Relumina

    Protein binding

    68–71%

    PubChem CID

    10348973

    MedlinePlus

    a621006

    ChEBI

    Not assigned

    ATC code

    L02BX04

    DrugBank

    DB11853

    KEGG

    D10888

    Routes of administration

    Oral

    Directions

    In contrast to many other hormone-suppressing therapies, Orgovyx is used in oral form. Each film-coated tablet contains 120 mg of relugolix. On the first day or when Orgovyx is interrupted for more than 7 days, take three tablets (360 mg) and continue with one daily tablet after. Make sure you take the medication at approximately the same time each day, with or without food. Do not crush or chew the tablets, but swallow them whole. If you miss a dose, take it as soon as you remember, but if more than 12 hours have passed, do not take another tablet until your next scheduled dose. Even if prostate cancer stops responding to the medication, it’s usually continued to keep testosterone levels low, which helps keep the cancer under control.

    Ingredients

    The active ingredient in Orgovyx is relugolix.

    Inactive ingredients are mannitol, sodium starch glycolate, hydroxypropyl cellulose, magnesium stearate, hypromellose, titanium dioxide, ferric oxide red, and carnauba wax.

    Cautions

    Before taking Orgovyx, inform your doctor of your complete medical history, all the medications and supplements you’re taking, as well as your allergies. This allows your provider to accurately assess your situation and ensure that Orgovyx is the right fit for you.

    Some medications can interfere with the way Orgovyx works. For example, this applies to certain heart, infection, or seizure medicines that may raise or lower Orgovyx levels in your body. Your doctor may adjust the timing or dose if none of these medications can be discontinued or replaced.

    Orgovyx may affect your heart rhythm by prolonging the QT interval. Therefore, it’s crucial to let your healthcare provider know if you have heart problems, electrolyte imbalances, or take medicines that affect the QT interval. They may check your ECG and electrolyte levels to ensure this medication is safe for your heart.

    If you notice allergy symptoms, such as rash, swelling, or trouble breathing, immediately seek medical help.

    Orgovyx can be harmful to an unborn baby. If you have a partner who can become pregnant, it’s crucial to use effective birth control during treatment and for 2 weeks after the last dose.

    Orgovyx may affect certain blood tests, such as reproductive hormone tests since it lowers hormone levels. Your doctor will monitor your PSA (Prostate-Specific Antigen) and may check testosterone if needed.

    Contraindications

    Do not take Orgovyx if you are severely allergic to relugolix or any of the above-named ingredients.

    Side Effects

    Patients using Orgovyx commonly report hot flashes or flushing, fatigue, muscle or joint pain, and decreased hemoglobin, reflected as anemia-like symptoms such as tiredness or shortness of breath, increased blood sugar levels, increased triglycerides, increased liver enzymes, constipation, diarrhea, or headache.

    Serious and much rarer side effects include serious heart rhythm problems, severe allergic reactions, heart attack or stroke, severe anemia (very low hemoglobin), very high blood sugar, and infertility or reduced fertility.

    This is not a complete list of all possible side effects. If you experience persistent or severe side effects of Orgovyx, contact your healthcare provider immediately.

    Looking to buy Orgovyx easily and stress-free here at Canada Pharmacy? All you need is a valid prescription from your doctor!

    References

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 15166

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