What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Periogard (Chlorhexidine)
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Product Details
Description
PerioGard (chlorhexidine gluconate oral rinse USP, 0.12%) is an oral rinse prescribed to treat gingivitis.
PerioGard is a blue liquid that comes in 16-ounce (473 mL) amber plastic bottles.
Fact Table
Formula
C22H30Cl2N10
License
US FDA
Bioavailability
Poorly absorbed through oral mucosa
Legal status
Prescription only (Rx)
Chemical Name
1,1'-Hexamethylene-bis(5-(p-chlorophenyl)biguanide) di-D-gluconate
Elimination half-life
10 hours (plasma)
Dosage (Strength)
0.12% solution
Pregnancy
Consult a doctor
Brands
Periogard, Peridex, Hibiclens
Protein binding
~87%
PubChem CID
9552076
MedlinePlus
a682947
ChEBI
CHEBI:3614
ATC code
A01AB03
DrugBank
DB00878
KEGG
D03772
Routes of administration
Oral rinse
Directions
Use PerioGard oral rinse as directed by your dentist. The recommended dose is to swish 15 mL in the mouth two times a day for 30 seconds, then spit it out.
Keep PerioGard stored between 20°C and 25°C (68°F and 77°F) and out of children’s reach.
For additional product use information, refer to the medication guide that comes with PerioGard.
If you have any questions or concerns, do not hesitate to reach out to your dentist.
Ingredients
The active ingredient in PerioGard is chlorhexidine gluconate.
The base includes water, propylene glycol, glycerin, sorbitol, polyoxyl 40 hydrogenated castor oil, flavor, cetylpyridinium chloride, and FD&C blue no. 1.
Contraindications
Patients with an allergy to chlorhexidine gluconate or to any of the other ingredients in PerioGard oral rinse should not use it.
Cautions
- Before you begin using PerioGard, talk to your dentist about:
- All the prescription and over-the-counter medications you take
- Any mouthwashes you use
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- PerioGard contains the following warnings and precautions:
- PerioGard’s effects on periodontitis are unknown
- It is unknown whether chlorhexidine gluconate causes an increase of subgingival calculus; calculus deposits should be removed at least every 6 months via dental prophylaxis
- Serious allergic reactions, including anaphylaxis, can occur
- PerioGard can stain teeth and other oral surfaces, restorations, and the tongue, which can be removed from most tooth surfaces via dental prophylaxis; however, staining can be permanent. Patients should not use PerioGard if staining is not acceptable
- Altered taste can occur
Side Effects
Staining of the teeth and other oral surfaces, increased calculus formation, and altered taste are common PerioGard side effects. Other side effects may also occur.
Immediately notify your dentist or doctor of any side effects that bother you or won’t go away.
You can buy PerioGard right here!
Reference
PerioGard. New York, NY: Colgate Oral Pharmaceuticals, Inc.; 2019.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 5399
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