What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Seebri (Glycopyrronium Bromide)
Prescription Required
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Product Details
Description
Seebri Breezhaler (glycopyrronium bromide) is used to alleviate symptoms of chronic obstructive pulmonary disease (COPD).
Seebri Breezhaler is an inhaler that uses a 50 mcg capsule.
Fact Table
Formula
C19H28BrNO3
License
US FDA, EMA
Bioavailability
40-45% (inhaled)
Legal status
Prescription only (Rx)
Chemical Name
[(RS)-3-(2-cyclopentyl-2-hydroxy-2-phenylacetoxy)-1,1-dimethylpyrrolidinium] bromide
Elimination half-life
33-53 hours (inhaled)
Dosage (Strength)
15.6 mcg per inhalation
Pregnancy
Consult a doctor
Brands
Seebri Breezhaler, Seebri Neohaler
Protein binding
38-41%
PubChem CID
11954392
MedlinePlus
a603029
ChEBI
CHEBI:59868
ATC code
R03BB06
DrugBank
DB00986
KEGG
D08095
Routes of administration
Inhalation
Directions
Use Seebri Breezhaler as instructed by your doctor. The recommended dose is to inhale the contents of one 50 mcg capsule with Seebri Breezhaler once daily. The capsule should not be swallowed.
Inhaler instructions:
- Place one capsule into the appropriate location inside the inhaler.
- Hold the inhaler upright and pierce the capsule once by pressing both side buttons at the same time. You should hear a noise indicating the capsule has been pierced.
- Let go of the buttons and breathe out fully.
- Place the mouthpiece in your mouth and breathe in quickly and deeply. You should hear a whirring noise, and you may taste the medication.
- Hold your breath for up to 5 seconds.
- Ensure the capsule is empty. If it is not empty, repeat the inhaler use process.
- Throw away the capsule when empty.
Keep the Seebri Breezhaler capsules in their blister; only remove immediately before using. Do not use past the expiration date. Store the capsules and inhaler away from children’s reach.
For further instructions for use, refer to the medication guide that comes with your Seebri Breezhaler prescription.
If you have any questions or concerns, contact your doctor or pharmacist.
Ingredients
The active ingredient in Seebri Breezhaler is glycopyrronium bromide.
Contraindications
Patients with an allergy to glycopyrronium or to any of the excipients in Seebri Breezhaler should not use it.
Cautions
- Before you begin treatment with Seebri Breezhaler, talk to your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Seebri Breezhaler is associated with the following warnings and precautions:
- Do not use Seebri Breezhaler as a rescue inhaler
- Allergic reactions have occurred
- Potentially life-threatening paradoxical bronchospasms can occur
- Caution should be used in patients with glaucoma or urinary retention
- Use only if the benefits outweigh the risks in patients with severe kidney problems
- Caution should be used in patients with a history of cardiovascular disease
- Patients with rare hereditary problems of galactose intolerance, glucose-galactose malabsorption, or Lapp lactase deficiency should avoid using Seebri Breezhaler
Side Effects
Dry mouth, gastroenteritis, and trouble sleeping are common Seebri Breezhaler side effects; however, patients may experience other side effects.
Immediately tell your doctor if you experience side effects that bother you or won’t go away.
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Reference
Seebri Breezhaler. Basel, Switzerland: Novartis Pharma AG; 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14931
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