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What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Serostim (Somatropin)
Prescription Required
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Product Details
Description
Serostim (somatropin) is an injectable medication given to increase lean body mass and body weight and improve physical endurance in HIV patients who have wasting or wasting syndrome.
Serostim is available in single-dose vials containing 5 mg or 6 mg. It is also available in multi-dose vials containing 4 mg.
Fact Table
Formula
C990H1528N262O300S7
License
US FDA
Bioavailability
70-90% (subcutaneous)
Legal status
Prescription only (Rx)
Chemical Name
Somatropin
Elimination half-life
2-4 hours (subcutaneous)
Dosage (Strength)
4 mg, 5 mg, 6 mg, and 8 mg vials
Pregnancy
Consult a doctor
Brands
Serostim, Humatrope, Norditropin, Genotropin, others
Protein binding
~40%
PubChem CID
16132342
MedlinePlus
a601020
ChEBI
CHEBI:82626
ATC code
H01AC01
DrugBank
DB00052
KEGG
D06086
Routes of administration
Subcutaneous injection
Directions
Use Serostim as directed by your doctor, who will determine an appropriate treatment regimen for you based on your weight.
A healthcare professional should teach you or a caregiver how to properly store, prepare, administer, and discard Serostim. The medication should be injected subcutaneously (underneath the skin) in the thigh, upper arm, abdomen, or buttock. Injection sites should be rotated with each injection in order to minimize the risk of local irritation.
Do not share Serostim products or needles with other people. Store away from children’s reach.
For further information regarding the use of Serostim, including storage details, refer to the medication guide that comes with your prescription.
If you have any questions or concerns, contact your doctor or pharmacist.
Ingredients
The active ingredient in Serostim is somatropin.
Contraindications
Patients who have any of the following conditions should not receive Serostim:
- Acute illness that is critical
- Cancer
- Diabetic retinopathy
- Allergy to somatropin or to any of the excipients in Serostim
Cautions
- Before you begin receiving Serostim injections, inform your doctor of:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health problems and past medical history
- Your pregnancy or breastfeeding status
- Serostim contains the following warnings and precautions:
- Increased death in patients with acute illness that is critical after undergoing open heart surgery, abdominal surgery, multiple accidental trauma, or with acute respiratory failure
- Patients with HIV should continue maintenance therapy with antiretrovirals while being treated with Serostim
- Tumor progression, recurrence, or development
- Diabetes or impaired glucose tolerance; glucose levels should be periodically monitored, and dose adjustments of diabetes medications may be needed
- Increased pressure inside the skull that can usually be reversed after stopping the medication or reducing the dose
- Serious allergic reactions
- Fluid retention
- Carpal tunnel syndrome
- Pancreatitis
Side Effects
The most common Serostim side effects are tissue turgor (fluid retention, muscle pain, numbness) and musculoskeletal discomfort (joint pain, pain in extremities). However, other side effects may also occur.
Immediately call your doctor if you experience side effects that bother you or won’t go away.
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Reference
Serostim. Rockland, MA: EMD Serono, Inc.; 2019.
Popular Questions
This product is primarily used to increase lean body mass and body weight and improve physical endurance in HIV patients who have wasting or wasting syndrome. This is valuable as it helps improve quality of life and overall health outcomes for individuals dealing with these conditions.
It is available in single-dose vials containing 5 mg or 6 mg, and in multi-dose vials containing 4 mg. Having multiple dosage options provides flexibility to healthcare providers to tailor treatments according to the specific needs of the patient.
The chemical formula is C990H1528N262O300S7. Understanding the formula is crucial for pharmacists and healthcare providers to ensure correct usage and compatibility with other treatments.
The bioavailability is between 70-90% when administered subcutaneously. High bioavailability means that a significant portion of the drug reaches the bloodstream, ensuring effective treatment.
The elimination half-life is 2-4 hours when administered subcutaneously. The half-life provides insight into how long the drug stays active in the body, which is important for scheduling doses.
It is administered via subcutaneous injection. Subcutaneous administration allows for slow and consistent absorption, which is beneficial for maintaining stable drug levels.
This product is available by prescription only (Rx). Prescription-only status ensures that use is monitored by healthcare professionals, which is crucial for safety and efficacy.
The protein binding is approximately 40%. Knowing the protein binding helps understand the drug's distribution in the body and potential interactions with other medications.
Available brands include Serostim, Humatrope, Norditropin, and Genotropin. Multiple brand options can provide patients with choices based on availability and insurance coverage.
View allThe PubChem CID is 16132342. This identifier is useful for researchers and healthcare professionals to access detailed chemical information.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 14604
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