What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Zoladex (Goserelin acetate)
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Product Details
Description
Zoladex is an injectable implant that is used to treat prostate cancer and endometriosis. It is also used to treat advanced breast cancer in women who have not undergone menopause or are around the time of menopause.
In addition, Zoladex is used as an endometrial-thinning agent before endometrial ablation.
Zoladex is available as an implant of 3.6 mg or 10.8 mg that is injected underneath the skin.
Zoladex is classified as a gonadotropin releasing hormone (GnRH) agonist.
Fact Table
Formula
C59H84N18O14
License
US FDA
Bioavailability
101.0%
Legal status
Rx-Only
Chemical Name
Goserelin
Elimination half-life
4–5 hours
Dosage (Strength)
Depot 3.6mg injection, Depot LA 10.8mg injection
Pregnancy
Should not be used
Brands
Zoladex
Protein binding
27.3%
PubChem CID
5311128
MedlinePlus
a601002
ChEBI
5523
ATC code
5523
DrugBank
DB00014
KEGG
D04405
Routes of administration
Implant
Directions
Zoladex should be administered as directed by your doctor. Questions or concerns may be directed to your doctor or pharmacist.
Patients generally receive a Zoladex injection underneath the skin every 28 days. Your doctor will tell you how long your treatment should last.
Ingredients
Zoladex contains 3.6 mg or 10.8 mg goserelin implant.
Contraindications
Do not use Zoladex if you are allergic to the medication.
Do not use Zoladex if you are pregnant unless you are receiving Zoladex to treat advanced breast cancer.
Cautions
- Before you begin treatment with Zoladex injection, inform your doctor of:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your health conditions and past medical history
- Your pregnancy or breastfeeding status
- Your tumor symptoms may worsen during the first few weeks of receiving Zoladex and may include blockages in the ureters and spinal cord compression.
- Men who receive GnRH analogs may develop high blood sugar and may become at risk for diabetes. Blood sugar levels should be monitored.
- Heart attacks, sudden cardiac death, and stroke have occurred in men who received treatment with GnRH analogs. Patients should be monitored.
- Patients with bone cancer who are receiving Zoladex may develop high calcium levels in the blood.
- Hypersensitivity reactions can occur in some patients who receive Zoladex.
- A heart rhythm disorder known as QT prolongation can occur with the use of Zoladex.
- Injection site reactions can occur with Zoladex administration.
- Depression or worsening depression may occur in women who use GnRH agonists.
- Cervical resistance can occur during treatment with Zoladex.
Side Effects
Common Zoladex side effects include hot flashes, headache, sweating, acne, mood changes, depression, decreased sex drive, vaginal inflammation, breast shrinkage, skin conditions, and swelling. However, other side effects may also occur. Call your doctor right away if you experience side effects that become bothersome or persistent.
Learn more about Zoladex and where to buy Zoladex at Canada Pharmacy.
References:
- Zoladex (goserelin implant) 3.6 mg. Deerfield, IL: TerSera Therapeutics LLC; 2023.
- Zoladex (goserelin implant) 10.8 mg. Deerfield, IL: TerSera Therapeutics LLC; 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 10549
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