Prescription Required
February 4, 2023 by Brenda E. (Texas, United States)
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Medically Reviewed
Please be aware that all information shared here at Canada Pharmacy has been medically reviewed and fact-checked for accuracy. These verifications are made by board-certified medical professionals who have the authority required to state that information related to medical conditions, symptoms, procedures and tests, and standard treatment protocols is valid and truthful. This is based on current guidelines and consensuses shared amongst medical professionals, and in representation of the latest research.
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
NIX 5% Dermal Cream (Permethrin)
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Product Details
Description
Nix (permethrin) 5% dermal cream is used on the skin to treat scabies, mites that infest the skin and cause itching and irritation.
Fact Table
Formula
C21H20Cl2O3
License
US DailyMed
Bioavailability
60%
Legal status
Rx-Only
Chemical Name
Permethrin
Elimination half-life
39.5 days
Dosage (Strength)
5%
Pregnancy
Appears to be safe
Brands
Nix
Protein binding
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PubChem CID
40326
MedlinePlus
-
ChEBI
34911
ATC code
P03AC04
DrugBank
DB04930
KEGG
C14388
Routes of administration
Topical
Directions
Be sure to read and carefully follow the instructions that come with Nix 5% dermal cream. Talk to your doctor or pharmacist about any questions or concerns you may have.
Nix 5% dermal cream is for use on the skin only. Do not get the cream in your eyes or mouth.
Apply the cream from head to toe. Leave it on for 8 to 14 hours, then rinse. It may be reapplied in 7 days if mites don't go away.
Ingredients
Nix dermal cream contains permethrin. Permethrin kills parasites like scabies.
Contraindications
- Nix 5% dermal cream should not be used in patients who are allergic to its ingredients.
- Nix 5% dermal cream should not be used in pediatric patients who are younger than 2 years old. Talk to a doctor before using Nix on a pediatric patient.
Cautions
- Before beginning treatment with Nix 5% dermal cream, talk to your doctor about the following:
- All the medications you take, including other topical creams, lotions, and ointments
- Your allergies
- Your medical history and current health problems
- If you are pregnant or breastfeeding
- Nix 5% dermal cream may temporarily worsen itching, swelling, and redness.
- Nix 5% dermal cream may cause breathing problems or an asthma attack in patients who have ragweed allergies.
Side Effects
Nix 5% dermal cream side effects may include burning, stinging, or itching.
Tell your doctor if bothersome or continuous side effects develop.
Reference:
- Medscape.Permethrin.
Popular Questions
Permethrin cream 5% is a topical medication primarily used to treat scabies, a skin infestation caused by mites. It works by paralyzing and killing the mites and their eggs, providing relief from itching and discomfort. It is also sometimes used to treat lice infestations.
A related product is Mycostatin Cream (Nystatin). Understanding related products can offer alternative treatment options for different skin conditions.
The active ingredient in the cream is permethrin. Permethrin is effective in killing parasites like scabies, providing relief from itching and irritation caused by mite infestations.
The strength of the cream is 5%. This concentration is effective in treating scabies by eliminating the mites responsible for the condition.
The cream should be applied from head to toe and left on for 8 to 14 hours before rinsing off. It may be reapplied in 7 days if mites persist. Proper application ensures maximum effectiveness in treating the condition.
The chemical formula for permethrin, the active ingredient, is C21H20Cl2O3. Understanding the chemical composition can help ensure the product's compatibility with other treatments and avoid potential allergic reactions.
The bioavailability of the cream is 60%. This indicates the proportion of the active ingredient that enters the circulation and is available for activity, ensuring effective treatment of scabies.
The elimination half-life of permethrin is 39.5 days. This duration impacts how long the compound stays active in the body, influencing dosing intervals and the persistence of its effects.
The legal status of the cream is Rx-Only, meaning it requires a prescription. This ensures that the product is used under medical supervision, which is important for safe and effective treatment.
View allThe cream is administered topically, meaning it is applied directly to the skin. Topical application targets the affected area directly, allowing for localized treatment of scabies.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 307
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