What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Protopic Ointment (Tacrolimus)

Brand

Protopic Ointment (Tacrolimus)

Prescription Required

Strength
Qty
0.03%
0.10%

Generic Equivalent - Protopic Ointment (Tacrolimus)

Prescription Required

Strength
Qty
0.03%
0.10%
  • Related Products & Conditions

  • Product Details

    Description

    Protopic Uses and Indications:

    Protopic Cream

    Protopic cream is used to treat a skin condition called eczema. Eczema is an allergic condition of skin in which red, irritated and itchy blisters or patches appear on the skin. This drug treats eczema by weakening the immune system of the skin. This drug belongs to a class of drugs called topical calcineurin inhibitors.

    You can purchase high-quality tacrolimus ointment online from Canada Pharmacy and enjoy reduced prices. Your order will be delivered right to your doorstep without a hassle.

    Fact Table

    Formula

    C44H69NO12

    License

    US FDA, EMA, PMDA (Japan)

    Bioavailability

    Minimal systemic absorption (topical use)

    Legal status

    Rx-only

    Chemical Name

    (1R,9S,12S,13R,14S,17R,18E,21S,23S,24R,25S,27R)-12-[(E)-1-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]prop-1-en-2-yl]-1,18-dihydroxy-13,14,22,28-tetramethoxy-17,23-dimethyl-11,15,29-trioxatetracyclo[23.3.1.04,9.05,7]triacont-18-ene-2,3,10,16-tetrone

    Elimination half-life

    ~8.7–11 hours (systemic, oral use)

    Dosage (Strength)

    0.03% and 0.1% topical ointment

    Pregnancy

    Category C – Risk cannot be ruled out

    Brands

    Protopic, Advagraf (oral use), generic tacrolimus ointments

    Protein binding

    ~99% (systemic use)

    PubChem CID

    445643

    MedlinePlus

    a601117

    ChEBI

    61049

    ATC code

    D11AH01 (topical)

    DrugBank

    DB00864

    KEGG

    D00111

    Routes of administration

    Topical (ointment), Oral (capsule), Intravenous

    Directions

    Thoroughly read the instructions leaflet provided by your pharmacist.

    Use this medication according to the prescription provided by your doctor.

    It is usually applied once or twice a day on the affected area. But you have to apply it according to the prescription given by your doctor. Strictly remember to wash your hands before and after the application of this ointment. This ointment is only for use on skin. Keep it away from your eyes, nose, and mouth. Do not apply to open wounds or areas which are infected. If accidentally, a contact occurs with open wounds, infected areas, mouth, nose or eyes, rinse those areas with a lot of water immediately.

    Ingredients

    The active Ingredient in Protopic cream is Tacrolimus, either 0.03% or 0.1%.

    Inactive ingredients include:

    • Mineral oil
    • Paraffin
    • Propylene carbonate
    • White petrolatum
    • White wax

    Cautions

    • Tell your doctor if you are allergic to this medication or other medications like sirolimus.
    • Inform your doctor about all the allergies you have.
    • Inform your doctor about your medical history of skin infections (e.g., herpes, shingles), other skin conditions, and kidney disease.
    • Do not use alcohol when using this medication.
    • Do not use this drug if you breastfeed an infant. It might have adverse effects on your child.
    • Reduce your exposure to the sun to the bare minimum when using this medication.
    • If you are pregnant, consult your doctor before taking this medication.

    Side Effects

    The side effects you should be aware of are:

    • Stinging
    • Burning
    • Soreness
    • Itching in the area of treated skin
    • Headache
    • Acne
    • Hair bumps (folliculitis)
    • Upset stomach
    • Flu-like symptoms (e.g., fever, chills, runny nose, sore throat, muscle aches),
    • Increased sensitivity of the skin to hot/cold/pain/touch may also occur.

    Questions & Answers
    avatar
    Popular Questions

    4 months ago
    4 months ago
    It is advised not to use alcohol while using this medication. Alcohol can interact with the drug and may exacerbate side effects or reduce its efficacy, so avoiding it ensures the treatment works as intended.
    4 months ago
    4 months ago
    The ointment works by weakening the immune system of the skin. This mechanism helps reduce the symptoms of eczema, such as inflammation and itching, providing relief to those affected by the condition.
    4 months ago
    4 months ago
    The ointment is typically applied once or twice a day on the affected area, as prescribed by a doctor. Following the application guidelines ensures the effectiveness of the treatment and minimizes the risk of side effects.
    4 months ago
    4 months ago
    When using tacrolimus, it's important to avoid grapefruit and grapefruit juice, as they can increase the drug's concentration in the bloodstream and potentially lead to toxicity. Additionally, avoid exposure to sunlight or UV light, as tacrolimus can make your skin more sensitive. Always inform your healthcare provider about any other medications or supplements you are taking, as there may be interactions. For further consultation, you can contact us at our toll-free number, 1-800-891-0844, or chat with us online. We are available 24 hours a day, 7 days a week.
    4 months ago
    4 months ago
    If you are allergic to this medication or similar drugs like sirolimus, you should inform your doctor. Being aware of potential allergies helps prevent adverse reactions and ensures a safe treatment experience.
    4 months ago
    4 months ago
    This ointment belongs to a class of drugs known as topical calcineurin inhibitors. These drugs are valuable as they specifically target the immune response in the skin, offering an effective treatment for eczema without the side effects of traditional steroids.
    4 months ago
    4 months ago
    The active ingredient is Tacrolimus, available in concentrations of either 0.03% or 0.1%. Tacrolimus is effective in reducing eczema symptoms by modulating the immune system response in the skin.
    4 months ago
    4 months ago
    This ointment is used to treat eczema, a skin condition characterized by red, irritated, and itchy blisters or patches. By treating eczema, the ointment helps alleviate discomfort and improve skin appearance, which can significantly enhance the quality of life for sufferers.
    4 months ago
    4 months ago
    No, this ointment should not be applied to open wounds or infected areas. Using it on such areas could lead to irritation or infection, which could worsen the condition instead of improving it.
    4 months ago
    4 months ago
    If the ointment accidentally contacts your eyes, nose, or mouth, you should rinse those areas with a lot of water immediately. Prompt rinsing helps prevent irritation or adverse reactions in sensitive areas.
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    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2420

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