Abevmy (Bevacizumab)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    Abevmy is a biologic drug used to treat metastatic colorectal cancer (mCRC), locally advanced, metastatic, or recurrent non-small cell lung cancer (NSCLC), malignant glioma, and other types of cancers.

    Abevmy works by binding to vascular endothelial growth factor (VEGF). VEGF is a protein on the surface of endothelial cells that increases the growth of blood vessels. Stopping the activity of VEGF reduces the growth of new blood vessels that feed tumors.

    Directions

    Abemvy should only be administered by a trained healthcare professional. Take it exactly as directed.

    Ingredients

    The active ingredient in Abevmy is bevacizumab.

    Interactions

    Common drug-drug interactions with this medication may include:

    • Alendronate
    • Bacillus Calmette-Guérin (BCG)
    • Belimumab
    • Carboplatin
    • Clozapine
    • Cyclophosphamide
    • Dipyrone
    • Doxorubicin
    • Etidronate
    • Ibandronate
    • Ifosfamide
    • Risedronate
    • Sorafenib
    • Sunitinib
    • Zoledronic acid

    Cautions

    Tell your doctor if you have a history of heart problems before starting this drug.

    Abevmy may cause serious side effects on the dermatologic, respiratory, gastrointestinal, neurologic, hematologic, and reproductive systems.

    Tell your doctor if you have a history of kidney or liver problems before starting this drug.

    Side Effects

    Common side effects may include:

    • Abdominal pain
    • Allergic reactions
    • Bleeding
    • Blood clots
    • Bronchitis
    • Bruising
    • Changes in moods
    • Changes in the sense of taste
    • Chest pain
    • Chills
    • Coughing
    • Diarrhea
    • Difficulty in sleeping
    • Excessive tearing
    • Fever
    • Headache
    • High blood pressure
    • Hoarseness
    • Infections
    • Joint pain
    • Loss of appetite
    • Lung infection
    • Mouth infection
    • Muscle pain
    • Nausea
    • Necrotizing fasciitis
    • Nephrotic syndrome
    • Nose infection
    • Pain
    • Pelvic pain
    • Protein in the urine
    • Rectal bleeding
    • Runny nose
    • Scaling skin or changes in skin color
    • Seizures
    • Shortness of breath
    • Sinus infection
    • Skin infection
    • Sores in the mouth
    • Stroke
    • Swelling and numbness of the hand and feet
    • Swelling of the hand and feet
    • Throat infection
    • Tingling sensation or numbness in toes and fingers
    • Tiredness
    • Trachea
    • Urine infection
    • Vision loss
    • Vomiting
    • Weight loss

    References

    Abemvy [package insert]. Etobicoke, ON: BGP Pharma ULC; Nov 2021.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 14432

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