What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Adcirca (Tadalafil)


Adcirca (Tadalafil)

Prescription Required


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Generic Equivalent - Adcirca (Tadalafil)

Prescription Required


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  • Product Details


    Adcirca is a prescription medication used to treat pulmonary arterial hypertension (PAH). Adcirca belongs to the class of medications called phosphodiesterase 5 inhibitors (PDE5). Adcirca has been shown to increase the ability to exercise in patients with PAH.

    PDE5 is an enzyme responsible for the breakdown of the chemical messenger cGMP. cGMP works by increasing the levels of nitric oxide, which relaxes the blood vessels of the lungs. Increasing blood flow to the lungs helps improve PAH symptoms and increase the ability to exercise.


    The usual dosage of Adcirca is 40 mg by mouth once daily. Do not divide the dose into more than one throughout the day unless directed otherwise by your healthcare provider.


    The active ingredient in Adcirca is tadalafil, which is also the name of Adcirca generic.


    Adcirca can interact with many medications. Tell your doctor and pharmacist about all medicines you are taking before starting Adcirca. Common interactions may include:

    • Abametapir
    • Alprostadil
    • Amyl nitrate
    • Apalutamide
    • Atazanavir
    • Carbamazepine
    • Ceritinib
    • Clarithromycin
    • Dapoxetine
    • Darunavir
    • Enzalutamide
    • Fosamprenavir
    • Fosphenytoin
    • Fusidic acid
    • Idelalisib
    • Indinavir
    • Itraconazole
    • Ketoconazole
    • Lonafarnib
    • Lopinavir
    • Lumacaftor
    • Lumacaftor-ivacaftor
    • Mifepristone
    • Mitotane
    • Nefazodone
    • Nelfinavir
    • Nitroprusside
    • Ombitasvir-paritaprevir-ritonavir
    • Organic nitrates (vasodilators)
    • Phenobarbital
    • Phenytoin
    • Posaconazole
    • Primidone
    • Rifampin (rifampicin)
    • Riociguat
    • Ritonavir
    • Saquinavir
    • Telithromycin
    • Tucatinib
    • Voriconazole


    Adcirca should not be taken with organic nitrates or guanylate cyclase (GC) stimulators.

    Tell your doctor if you have a history of low blood pressure (hypotension).

    Adcirca and similar medications have been known to rarely affect vision and hearing.

    Side Effects

    Common Adcirca side effects may include:

    • Back pain
    • Diaphoresis
    • Dizziness
    • Dyspepsia
    • Flushing
    • Headache
    • Hearing loss
    • Hypertension
    • Increased liver enzymes
    • Limb pain
    • Myalgia
    • Nasal congestion
    • Nasopharyngitis
    • Nausea
    • Prolonged erection
    • Rectal hemorrhage
    • Renal insufficiency
    • Respiratory tract infection
    • Skin rash
    • Tinnitus
    • Urinary tract infection


    Adcirca [package insert]. Indianapolis, IN: Eli Lilly; 2020.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 11443

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