Afrezza (Insulin)

What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    AFREZZA (inhaled insulin) is a prescription medication used to improve blood sugar control in people with diabetes mellitus. AFREZZA can be used in people with type 1 diabetes of type 2 diabetes.

    AFREZZA insulin is an inhaled insulin product. It is a good option for people who prefer not to self-inject their insulin.

    Directions

    Inhale the contents of the cartridge(s) using a single inhalation per cartridge. AFREZZA should be taken at the beginning of a meal, and the dose must be individualized based on blood sugar readings.

    AFREZZA cartridges come in the following strengths:

    • 4 unit cartridge
    • 8 unit cartridge

    Ingredients

    The active ingredient in AFREZZA is human insulin.

    Interactions

    Some medications can raise or lower blood sugar in people with diabetes. When taking AFREZZA with these medications, the dose may need to be adjusted based on blood sugar readings. Example include:

    • Alcohol
    • Atypical Antipsychotics
    • Corticosteroids
    • Disopyramide
    • Diuretics
    • Estrogens/Progesterones
    • Fibrates
    • Fluoxetine
    • Isoniazid
    • Lithium
    • Monoamine Oxidase Inhibitors (MAOIs)
    • Niacin
    • Oral antidiabetic agents
    • Pentoxifylline
    • Phenothiazine derivatives
    • Pramlintide
    • Propoxyphene
    • Protease inhibitors
    • Salicylates
    • Somatostatin Analogues
    • Somatropin
    • Sulfonamide Antibiotics
    • Sympathomimetic agents
    • Thyroid replacement medication

    Cautions

    AFREZZA is contraindicated in people with asthma or chronic obstructive pulmonary disease (COPD). It can cause acute bronchospasm in these patients.

    Patients who smoke should not use AFREZZA.

    Patients with type 1 diabetes mellitus must use AFREZZA in combination with a long-acting insulin.

    AFREZZA cannot be used to treat diabetic ketoacidosis.

    Monitor blood sugar frequently when taking any insulin product. Your dose may need to be adjusted when there are changes to diet or exercise.

    Tell your doctor if you have a history of heart disease, liver disease, or kidney disease.

    Side Effects

    Common side effects with AFREZZA may include:

    • Cough
    • Hypoglycemia
    • Throat irritation
    • Throat pain

    References

    Afrezza [package insert]. Danbury, CT: MannKind; 2014.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13375

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