Description
Amoxicillin + potassium clavulanate is a prescription broad-spectrum antibiotic for pets. While it’s approved for cats and dogs in certain strengths, the 200 mg/50 mg strength described on this page is approved for dogs only. It treats skin infections, such as wounds, abscesses, cellulitis, and pyoderma, dental infections, and other bacterial soft-tissue infections.
This medication disrupts the formation of bacterial cell walls, leading to bacterial death. In addition, it blocks enzymes (ß-lactamases) used by some bacteria to resist antibiotics, making the drug more effective against a wide variety of bacteria.
| Fact Table |
| Formula |
C24H27KN4O10S |
| License |
US FDA |
| Bioavailability |
Well absorbed orally; absolute bioavailability not established |
| Legal status |
Rx-only |
| Chemical Name |
Amoxicillin and potassium clavulanate |
| Elimination half-life |
Amoxicillin: 1.3 hours; clavulanic acid: 1 hour |
| Dosage (Strength) |
250/125 mg, 500/125 mg, 875/125 mg tablets; 125/31.25 mg, 200/28.5 mg, 250/62.5 mg, 400/57 mg per 5 mL oral suspension |
| Pregnancy |
Consult a doctor |
| Brands |
Augmentin, Amoclan, Clavulin, Co-amoxiclav |
| Protein binding |
Amoxicillin: approximately 18%; clavulanic acid: approximately 25% |
| PubChem CID |
23695837 |
| MedlinePlus |
a685024 |
| ChEBI |
2677 |
| ATC code |
J01CR02 |
| DrugBank |
Amoxicillin: DB01060 / Clavulanic acid: DB00766 |
| KEGG |
D06485 |
| Routes of administration |
Oral |
Directions
You can buy amoxicillin + potassium clavulanate tablets in 200 mg/50 mg strength with a valid prescription at Canada Pharmacy. Always follow your veterinarian's directions when giving your dog this medication. They will determine your dog’s dosing schedule based on the condition treated, their weight, their body’s response to the medication, and other factors.
Veterinarians typically prescribe a dosage of 6.25 mg per pound of body weight, which should be administered every 12 hours. If your dog has a skin or soft-tissue infection, such as infected wounds or abscesses, they are usually prescribed amoxicillin + potassium clavulanate tablets for 5–7 days or for 48 hours after symptoms have resolved.
Deep bacterial skin infections (pyoderma) may need treatment for up to 21 days. According to the FDA-approved label, treatment should not exceed 30 days. Your veterinarian will determine the appropriate duration of therapy for your dog.
Amoxicillin + potassium clavulanate tablets should be given by mouth twice daily, with or without food. However, stomach upset may be prevented or reduced if you combine the medication with a small meal or treat.
Ingredients
The active ingredients in this medication are amoxicillin (a penicillin-type antibiotic) and clavulanate potassium (ß-lactamase inhibitor).
Cautions
Amoxicillin + potassium clavulanate tablets should only be given under the supervision of a licensed veterinarian.
Do not skip doses or stop early unless advised, as this may lead to treatment failure or bacterial resistance. Incorrect dosing can reduce effectiveness or increase side effects.
Inform your veterinarian of any medical conditions, medications, or allergies your dog has.
Let your veterinarian know if your dog is pregnant or breeding, as safety has not been established, and this medication is typically not recommended in these situations.
Stop use and contact a veterinarian immediately if your dog shows signs of an allergic reaction, which may be life-threatening in the most severe cases.
Notify your veterinarian if your dog experiences severe or persistent vomiting, diarrhea, or other stomach upset.
Keep out of reach of children and other animals.
Contraindications
Do not use in animals with a history of allergic reactions to penicillins or cephalosporins.
Side Effects
Relatively common, mild, and temporary side effects include soft stool, mild diarrhea, loss of appetite, vomiting, reduced energy, drooling, and lip-smacking after taking the tablet.
More serious and less common side effects include severe or persistent vomiting or diarrhea, liver-related effects like jaundice or weakness (rare). Allergic reactions, including itching, facial swelling, trouble breathing, and in rare cases, anaphylaxis, may also happen.
This is not a complete list of side effects. Reach out to your veterinarian if you notice any persistent or worrisome side effects from amoxicillin + potassium clavulanate.
Buy amoxicillin + potassium clavulanate tablets at Canada Pharmacy at a low cost with a valid prescription from your veterinarian!
References
-
Amoxicillin trihydrate and clavulanate potassium tablets. (2016). [VETERINARY TABLETS].
Reference Source
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IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 15295
Prescription Required
