What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Ampicillin (Generic)

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Generic Equivalent - Ampicillin (Generic)

Prescription Required

Strength
Qty
250mg
500mg

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  • Product Details

    Description

    Ampicillin is a prescription antibiotic used to treat different types of bacterial infections. It is more commonly used as a step down after intravenous (IV) ampicillin to continue treatment of an ongoing infection.

    The oral (capsule) version is indicated to treat:

    • Gastrointestinal infections
    • Genitourinary infections
    • Respiratory tract infections

    Ampicillin belongs to the penicillin family of antibacterial agents. It works by preventing bacteria from forming a bacterial cell wall. Without a cell wall, the bacteria's natural protection breaks down, and they stop growing.

    Fact Table

    Formula

    C16H19N3O4S

    License

    US FDA, EU EMA

    Bioavailability

    62% ±17%

    Legal status

    Rx-only

    Chemical Name

    Ampicillin

    Elimination half-life

    1 hour

    Dosage (Strength)

    250mg, 500mg

    Pregnancy

    No Known Risk

    Brands

    Generic

    Protein binding

    15 to 25%

    PubChem CID

    6249

    MedlinePlus

    a685002

    ChEBI

    28971

    ATC code

    J01CA01

    DrugBank

    DB00415

    KEGG

    D00204

    Routes of administration

    By mouth

    Directions

    Take ampicillin exactly as directed by your healthcare provider. The dose will vary depending on the type and severity of the infection.

    The normal ampicillin dose is three to four times per day.

    Ampicillin is available in 250 mg and 500 mg capsules.

    Ingredients

    Ampicillin is a generic drug, and the active ingredient is ampicillin.

    Interactions

    Ampicillin has many potential drug-drug interactions. Tell your doctor and pharmacist about everything you are taking before starting this medication. Common interactions include:

    • Allopurinol
    • Aminoglycosides
    • Atenolol
    • BCG
    • Chloroquine
    • Cholera vaccine
    • Dichlorphenamide
    • Lactobacillus and Estriol
    • Lanthanum
    • Methotrexate
    • Mycophenolate
    • Probenecid
    • Sodium picosulfate
    • Tetracycline
    • Typhoid vaccines
    • Warfarin

    Cautions

    A rash is a common side effect of ampicillin and is commonly confused with a hypersensitivity reaction (allergic reaction). Your healthcare provider should carefully evaluate the rash if it develops.

    Use caution if you have kidney problems.

    Long-term use of ampicillin can cause the bacterial infection C.diff. Tell your doctor if you have prolonged severe diarrhea while using this medication.

    Side Effects

    The most common Ampicillin side effects may include:

    • Agranulocytosis
    • Anemia
    • Diarrhea
    • Dysgeusia
    • Enterocolitis
    • Eosinophilia
    • Erythema multiforme
    • Exfoliative dermatitis
    • Fever
    • Glossalgia
    • Glossitis
    • Hemolytic anemia
    • Immune thrombocytopenia
    • Increased liver enzymes
    • Interstitial nephritis
    • Leukopenia
    • Melanoglossia
    • Nausea
    • Oral candidiasis
    • Penicillin-induced brain disease
    • Pseudomembranous colitis
    • Seizure
    • Serum sickness-like reaction
    • Skin rash
    • Sore mouth
    • Stomatitis
    • Stridor
    • Urticaria
    • Vomiting

    References

    1. Ampicillin [package insert]. Princeton, NJ: Sandoz; 2020.


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 11953

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