Description
Apoquel (oclacitinib maleate) is used by or on the order of a licensed veterinarian to treat itchiness due to allergic dermatitis and to manage atopic dermatitis in dogs that are 12 months old or older.
Fact Table |
Formula |
C15H23N5O2S |
License |
US FDA |
Bioavailability |
89% |
Legal status |
Rx-only |
Chemical Name |
Oclacitinib |
Elimination half-life |
3.1–5.2 hours |
Dosage (Strength) |
3.6mg, 5.4mg, 16mg |
Pregnancy |
Do not use |
Brands |
Apoquel |
Protein binding |
66.3–69.7% |
PubChem CID |
44631938 |
MedlinePlus |
- |
ChEBI |
- |
ATC code |
QD11AH90 |
DrugBank |
DB11441 |
KEGG |
D10141 |
Routes of administration |
By mouth |
Directions
Follow your veterinarian's instructions for administering Apoquel to your dog. Apoquel is dosed based on weight, so be sure to talk to your veterinarian about the appropriate dose for your dog. If you have any questions or concerns, reach out to your veterinarian or pharmacist.
Apoquel comes in tablets and the dosing is between 0.18 mg and 0.27 mg per pound of your dog's body weight. Give by mouth two times a day with or without food for up to 2 weeks, then give by mouth once daily for maintenance.
Ingredients
Olacitinib is the active ingredient contained in Apoquel.
Cautions
- Before you give Apoquel to your dog, be sure to discuss the following with your veterinarian:
- Your dog's medications
- Your dog's allergies
- Your dog's medical history and health conditions
- Your dog's pregnancy or nursing status
- Apoquel is for use in dogs only. Do not give Apoquel to humans. Keep the medication away from children and other animals.
- Apoquel should not be given to dogs younger than 12 months old.
- Apoquel should not be given to dogs with severe infections.
- Apoquel can increase your dog's risk for infection or for new neoplastic conditions. Apoquel may worsen existing neoplastic conditions.
- Apoquel should not be used in dogs that are breeding, pregnant, or nursing.
Side Effects
Apoquel side effects may include diarrhea, vomiting, anorexia, new cutaneous or subcutaneous lump, weakness, and excessive thirst. If you notice side effects in your dog that concern you or won't go away, call your veterinarian right away.
Reference:
Apoquel (oclacitinib tablet). Kalamazoo, MI: Zoetis Inc.; 2020.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13504