What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Apoquel (Oclacitinib)
Prescription Required
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Product Details
Description
Apoquel (oclacitinib maleate) is used by or on the order of a licensed veterinarian to treat itchiness due to allergic dermatitis and to manage atopic dermatitis in dogs that are 12 months old or older.
Fact Table
Formula
C15H23N5O2S
License
US FDA
Bioavailability
89%
Legal status
Rx-only
Chemical Name
Oclacitinib
Elimination half-life
3.1–5.2 hours
Dosage (Strength)
3.6mg, 5.4mg, 16mg
Pregnancy
Do not use
Brands
Apoquel
Protein binding
66.3–69.7%
PubChem CID
44631938
MedlinePlus
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ChEBI
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ATC code
QD11AH90
DrugBank
DB11441
KEGG
D10141
Routes of administration
By mouth
Directions
Follow your veterinarian's instructions for administering Apoquel to your dog. Apoquel is dosed based on weight, so be sure to talk to your veterinarian about the appropriate dose for your dog. If you have any questions or concerns, reach out to your veterinarian or pharmacist.
Apoquel comes in tablets and the dosing is between 0.18 mg and 0.27 mg per pound of your dog's body weight. Give by mouth two times a day with or without food for up to 2 weeks, then give by mouth once daily for maintenance.
Ingredients
Olacitinib is the active ingredient contained in Apoquel.
Cautions
- Before you give Apoquel to your dog, be sure to discuss the following with your veterinarian:
- Your dog's medications
- Your dog's allergies
- Your dog's medical history and health conditions
- Your dog's pregnancy or nursing status
- Apoquel is for use in dogs only. Do not give Apoquel to humans. Keep the medication away from children and other animals.
- Apoquel should not be given to dogs younger than 12 months old.
- Apoquel should not be given to dogs with severe infections.
- Apoquel can increase your dog's risk for infection or for new neoplastic conditions. Apoquel may worsen existing neoplastic conditions.
- Apoquel should not be used in dogs that are breeding, pregnant, or nursing.
Side Effects
Apoquel side effects may include diarrhea, vomiting, anorexia, new cutaneous or subcutaneous lump, weakness, and excessive thirst. If you notice side effects in your dog that concern you or won't go away, call your veterinarian right away.
Reference:
Apoquel (oclacitinib tablet). Kalamazoo, MI: Zoetis Inc.; 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13504
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