What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Aptiom (Eslicarbazepine acetate)
Generic Equivalent - Aptiom (Eslicarbazepine acetate)
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Product Details
Description
Aptiom is a prescription drug for the treatment of partial-onset seizures. Partial-onset seizures are abnormal electrical activity where the signals are not transmitted correctly in the brain. As opposed to other types of seizures, partial-onset only occurs in one part of the brain. Typically a person does not lose consciousness with this type of seizure.
Fact Table
Formula
C17H16N2O3
License
EU EMA, AU
Bioavailability
High bioavailability and reaches peak serum concentration 1-4 hours after a given dose
Legal status
RX Only
Chemical Name
Eslicarbazepine Acetate
Elimination half-life
10-20 hours
Dosage (Strength)
200mg (30 tablets), 400mg (30 tablets), 600mg (60 tablets)
Pregnancy
Consult a doctor
Brands
Aptiom
Protein binding
~30%
PubChem CID
179344
MedlinePlus
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ChEBI
87016
ATC code
N03AF04
DrugBank
DB09119
KEGG
D09612
Routes of administration
Oral
Directions
The starting dosage is 400 mg by mouth once daily. This may be increased to 800 mg once daily after one week or 1200 mg once daily after two weeks.
Ingredients
The active ingredient in Aptiom is eslicarbazepine acetate.
Interactions
Common drug-drug interactions may include:
- Abemaciclib
- Antihepaciviral Combination Products
- Asunaprevir
- Avacopan
- Avanafil
- Avapritinib
- Axitinib
- Bedaquiline
- Bosutinib
- Capmatinib
- Cariprazine
- Cobimetinib
- Daridorexant
- Dasabuvir
- Deflazacort
- DOXOrubicin
- Elbasvir and Grazoprevir
- Encorafenib
- Entrectinib
- Fedratinib
- Fexinidazole
- Finerenone
- Flibanserin
- Ibrexafungerp
- Infigratinib
- Ivabradine
- Lemborexant
- Lonafarnib
- Lumateperone
- Lurbinectedin
- Mavacamten
- Mobocertinib
- Neratinib
- Nisoldipine
- Olaparib
- Olutasidenib
- Orelabrutinib
- Oxcarbazepine
- Pacritinib
- Pemigatinib
- Pimavanserin
- Pretomanid
- Ranolazine
- Rimegepant
- Selpercatinib
- Selumetinib
- Simeprevir
- Sonidegib
- Tazemetostat
- Ulipristal
- Velpatasvir
- Venetoclax
- Voclosporin
- Vonoprazan
- Vorapaxar
- Voxilaprevir
- Zanubrutinib
Cautions
Tell your doctor if you have suicidal thoughts while starting this drug.
Tell your doctor if you experience any skin reactions while starting this medication.
Ask your doctor or pharmacist for a full list of precautions.
Side Effects
The most common side effects may include the following:
- Abdominal pain
- Abnormal gait
- Agranulocytosis
- Anaphylaxis
- Angioedema
- Ataxia
- Blurred vision
- Cognitive dysfunction
- Constipation
- Cough
- Decreased hematocrit
- Decreased hemoglobin
- Decreased T3 level
- Decreased T4
- Decreased visual acuity
- Depression
- Diarrhea
- Diplopia
- Dizziness
- DRESS syndrome
- Drowsiness
- Dysarthria
- Equilibrium disturbance
- Falling
- Fatigue
- Gastritis
- Headache
- Hypercholesterolemia
- Hypertension
- Hypochloremia
- Hyponatremia
- Increased creatine phosphokinase
- Increased LDL cholesterol
- Increased serum bilirubin
- Increased serum transaminases
- Increased serum triglycerides
- Insomnia
- Leukopenia
- Megaloblastic anemia
- Memory impairment
- Nausea
- Nystagmus
- Pancytopenia
- Peripheral edema
- Prolongation P-R interval on ECG
- Severe dermatological reaction
- SIADH
- Skin rash
- Stevens-Johnson syndrome
- Thrombocytopenia
- Toxic epidermal necrolysis
- Tremor
- Urinary tract infection
- Vertigo
- Vomiting
- Weakness
References
Aptiom [package insert]. Marlborough, MA: Sunovion Pharmaceuticals Inc.; 2013.
Frequently Asked Questions about Aptiom (Eslicarbazepine acetate)
What is Aptiom (Eslicarbazepine acetate)?
Aptiom is a prescription medication containing the active ingredient Eslicarbazepine acetate. It is primarily used to treat certain types of seizures in people with epilepsy.
How does Aptiom work?
Aptiom works by reducing the abnormal electrical activity in the brain, which can lead to seizures. It does this by affecting sodium channels in nerve cells, which play a crucial role in the generation and transmission of electrical signals in the brain.
How should I take Aptiom?
Always take Aptiom exactly as prescribed by your doctor. Do not change the dose or stop taking the medication without consulting your healthcare provider.
Are there any side effects associated with Aptiom?
Yes, like all medications, Aptiom can cause side effects. Common side effects include dizziness, drowsiness, headache, nausea, and double vision. It's essential to discuss any concerns with your doctor.
Can I take Aptiom with other medications?
Some medications can interact with Aptiom, affecting its efficacy or increasing the risk of side effects. Always inform your doctor about all the medicines you are taking, including over-the-counter drugs, vitamins, and herbal supplements.
Is it safe to take Aptiom during pregnancy?
If you are pregnant or planning to become pregnant, discuss the risks and benefits of taking Aptiom with your doctor. It's essential to control seizures during pregnancy, but some antiseizure medications can pose risks to the unborn child.
Can I drink alcohol while taking Aptiom?
Alcohol can increase the risk of side effects such as dizziness and drowsiness when taken with Aptiom. It's best to discuss with your doctor about alcohol consumption while on this medication.
What should I do if I miss a dose?
If you miss a dose of Aptiom, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for the missed one.
How should I store Aptiom?
Store Aptiom at room temperature, away from moisture and heat. Keep it out of reach of children.
What should I do in case of an overdose?
If you suspect an overdose, seek emergency medical attention immediately or call your local poison control center.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13260
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