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What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Austedo XR (Deutrabenazine)

Brand

Austedo XR (Deutrabenazine)

Prescription Required

Strength
Qty
6mg
12mg
24mg
Titration Kit (6mg, 12mg, 24mg)

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  • Product Details

    Description

    Austedo XR (deutetrabenazine extended-release) is a prescription medicine designed to manage involuntary movements in patients with Huntington’s disease chorea and tardive dyskinesia. The extended-release formula allows once-daily dosing, offering convenience and steady symptom control throughout the day. Austedo XR uses include improving motor control, reducing abnormal movements, and enhancing overall quality of life for patients living with these neurological conditions. By regulating dopamine activity in the brain, Austedo XR helps restore balance and decrease the excessive movements that interfere with daily living.

    Fact Table

    Formula

    C19H21D6NO3

    License

    US DailyMed

    Bioavailability

    less than 10%

    Legal status

    Prescription Required

    Chemical Name

    Deutetrabenazine

    Elimination half-life

    9–10 hours

    Dosage (Strength)

    6mg, 12mg, 24mg, Titration Kit (6mg, 12mg, 24mg)

    Pregnancy

    Consult a doctor - safety in human pregnancy is unknown

    Brands

    Austedo XR

    Protein binding

    60–65% bound to plasma proteins

    PubChem CID

    73437646

    MedlinePlus

    a617022

    ChEBI

    Unknown

    ATC code

    N07XX16

    DrugBank

    DB12161

    KEGG

    D10701

    Routes of administration

    Oral (by mouth)

    Directions

    Austedo XR dosing is typically started at a low level and gradually increased under medical supervision to reach an effective dose that balances benefits with tolerability. The tablets are taken once daily with food to ensure proper absorption. Patients should not split, crush, or chew the tablets. Always follow your doctor’s instructions and do not adjust your dose without consulting your healthcare provider. The specific Austedo XR dosing schedule may vary depending on whether it is prescribed for Huntington’s chorea or tardive dyskinesia.

    Ingredients

    The active ingredient in Austedo XR is deutetrabenazine. Each extended-release tablet also contains inactive ingredients that may include lactose monohydrate, microcrystalline cellulose, magnesium stearate, and coating agents that help with absorption and stability. These components are carefully formulated to provide consistent release of medication throughout the day.

    Interactions

    Austedo XR can interact with certain medicines, including monoamine oxidase inhibitors (MAOIs), reserpine, strong CYP2D6 inhibitors, and alcohol. Combining Austedo XR with other medications that affect dopamine or serotonin may increase the risk of side effects. Always provide your healthcare professional with a full list of prescriptions, supplements, and over-the-counter products before starting Austedo XR.

    Cautions

    Patients should inform their doctor about any history of depression, suicidal thoughts, liver disease, or irregular heart rhythms before beginning treatment. Austedo XR may cause drowsiness, so caution is advised when driving or operating machinery until you know how the medicine affects you. This medication may not be suitable for individuals with untreated depression or severe hepatic impairment. Pregnant and breastfeeding women should consult their healthcare provider before using this medication.

    Side Effects

    Austedo XR side effects may include sleepiness, fatigue, diarrhea, and dry mouth. Some patients may also experience restlessness, insomnia, or mood changes. Rare but serious side effects include worsening depression or suicidal thoughts, which require immediate medical attention. Most Austedo XR side effects are mild to moderate and can often be managed by adjusting the dose under medical supervision.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 15440

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