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What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Azulfidine EN (Sulfasalazine) Delayed Release
Brand
Azulfidine EN (Sulfasalazine) Delayed Release
Prescription Required
Strength
Qty
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Generic Equivalent - Azulfidine EN (Sulfasalazine) Delayed Release
Prescription Required
Strength
Qty
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Related Products
Product Details
Description
Your doctor may prescribe Azulfidine EN to treat a variety of different autoimmune conditions. It is commonly prescribed for rheumatoid arthritis (RA), ulcerative colitis (UC), ankylosing spondylitis (off-label), Crohn’s disease (off-label), and psoriatic arthritis.
Azulfidine works by suppressing overacting cells of the immune system that are causing inflammation.
Fact Table
Formula
C18H14N4O5S
License
US FDA
Bioavailability
Less than 15%
Legal status
Rx-only
Chemical Name
Sulfasalazine
Elimination half-life
5-10 hours
Dosage (Strength)
500mg
Pregnancy
Safe
Brands
Azulfidine
Protein binding
More than 99.3%
PubChem CID
5339
MedlinePlus
a682204
ChEBI
9334
ATC code
A07EC01
DrugBank
DB00795
KEGG
D00448
Routes of administration
By mouth
Directions
Azulfidine can be taken with or without food. The tablets have an enteric coating, so they cannot be chewed, crushed, or split. They should be swallowed whole. The enteric coating ensures that the active ingredient is not broken down by stomach acid and reaches the area where it is needed in the intestines.
Rheumatoid arthritis (RA): Starting dose is 500 once or twice a day. The dose may be increased to 1000 mg twice daily for 12 weeks.
Ulcerative colitis (UC): Starting dose is 3000-4000 mg per day until in remission, and then 2000 mg per day.
Ankylosing spondylitis (off-label): 500-3000 mg per day in divided doses.
Crohn's disease (off-label): 3000-6000 mg per day in divided doses for up to 16 weeks.
Psoriatic arthritis (off-label): 500-3000 mg per day in divided doses.
Ingredients
The active ingredient in Azulfidine EN is sulfasalazine.
Interactions
Common drug-drug interactions may include:
Cardiac Glycosides
Dapsone (Topical)
Eltrombopag
Folic Acid
Local Anesthetics
Methenamine
Methotrexate
Methylfolate
Nitric Oxide
Nonsteroidal Anti-Inflammatory Agents
Prilocaine
Sodium Nitrite
Thiopurine Analogs
Warfarin
Cautions
Tell your doctor if you have a history of liver or kidney problems, G6PD deficiency, or asthma.
Do not use Asulfizine EN if you have a sulfa allergy.
Ask your doctor and pharmacist about all warnings that apply to you.
Side Effects
Azulfidine side effects may include the following:
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 12802
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Prescription Required
