What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Azulfidine EN (Sulfasalazine) Delayed Release


Azulfidine EN (Sulfasalazine) Delayed Release

Prescription Required


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Generic Equivalent - Azulfidine EN (Sulfasalazine) Delayed Release

Prescription Required

500mg (Enteric Coated)

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  • Product Details


    Your doctor may prescribe Azulfidine EN to treat a variety of different autoimmune conditions. It is commonly prescribed for rheumatoid arthritis (RA), ulcerative colitis (UC), ankylosing spondylitis (off-label), Crohn’s disease (off-label), and psoriatic arthritis.

    Azulfidine works by suppressing overacting cells of the immune system that are causing inflammation.


    Azulfidine can be taken with or without food. The tablets have an enteric coating, so they cannot be chewed, crushed, or split. They should be swallowed whole. The enteric coating ensures that the active ingredient is not broken down by stomach acid and reaches the area where it is needed in the intestines.

    • Rheumatoid arthritis (RA): Starting dose is 500 once or twice a day. The dose may be increased to 1000 mg twice daily for 12 weeks.
    • Ulcerative colitis (UC): Starting dose is 3000-4000 mg per day until in remission, and then 2000 mg per day.
    • Ankylosing spondylitis (off-label): 500-3000 mg per day in divided doses.
    • Crohn’s disease (off-label): 3000-6000 mg per day in divided doses for up to 16 weeks.
    • Psoriatic arthritis (off-label): 500-3000 mg per day in divided doses.


    The active ingredient in Azulfidine EN is sulfasalazine.


    Common drug-drug interactions may include:

    • Cardiac Glycosides
    • Dapsone (Topical)
    • Eltrombopag
    • Folic Acid
    • Local Anesthetics
    • Methenamine
    • Methotrexate
    • Methylfolate
    • Nitric Oxide
    • Nonsteroidal Anti-Inflammatory Agents
    • Prilocaine
    • Sodium Nitrite
    • Thiopurine Analogs
    • Warfarin


    Tell your doctor if you have a history of liver or kidney problems, G6PD deficiency, or asthma.

    Do not use Asulfizine EN if you have a sulfa allergy.

    Ask your doctor and pharmacist about all warnings that apply to you.

    Side Effects

    Azulfidine side effects may include the following:

    • Abdominal pain
    • Abnormal liver function tests
    • Anorexia
    • Cyanosis
    • Dizziness
    • Dyspepsia
    • Fever
    • Gastric distress
    • Headache
    • Hemolytic anemia
    • Leukopenia
    • Nausea
    • Oligospermia
    • Pruritus
    • Skin rash
    • Stomatitis
    • Thrombocytopenia
    • Urticaria
    • Vomiting

    Buy Azulfidine EN online from Canada Pharmacy with a valid prescription.


    Azulfidine EN [package insert]. New York, NY: Pfizer; 2012.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 12802

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