A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
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Bactroban is a nasal ointment used for the treatment of nasal colonization of methicillin-resistant Staphylococcus aureus (MRSA). It can be used by adults, pediatric patients, and healthcare workers to prevent the spread of MRSA institutional outbreaks in high-risk locations.
Bactroban works by binding to bacterial isoleucyl-transfer RNA (tRNA) synthetase. This protein is important for the replication of bacterial cells. At concentrations in this formulation, Bactroban is bactericidal (kills bacterial cells).
Bactroban is no longer available in the United States due to supply shortages.
Apply Bactroban nasal ointment into each nostril twice daily for 5-10 days or as directed by your healthcare provider.
Apply Bactroban nasal ointment to a clean dry area.
Do not get the ointment into the eyes or other mucus membranes.
The active ingredient in Bactroban is mupirocin.
There are no known significant interactions.
Do not mix Bactroban Nasal Ointment with other topical medications prior to administration. Mixing it with other medications may cause it to not work as well.
If Bactroban causes irritation at the application site, stop using it and tell your doctor right away.
Do not take Bactroban for longer or shorter than prescribed.
Use caution if you have a history of kidney problems.
Tell your doctor if you have an allergy to benzyl alcohol or polyethylene glycol before using this drug.
The most common side effects of this medication can include:
Bactroban Nasal Ointment [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2017.