What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Baraclude (Entecavir)
Prescription Required
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Product Details
Description
Baraclude is an antiviral medication that your doctor may prescribe to treat acute or chronic hepatitis B infection. Baraclude is typically a long-term medication that helps to suppress the development of hepatitis B infection.
Baraclude works by incorporating into the proteins that are necessary for hepatitis B viral particles to replicate themselves. Incorporating these proteins prevents the replication of viruses and slows down the infection to give the immune system a better chance to fight the infection.
Fact Table
Formula
C12H15N5O3
License
US FDA, EU
Bioavailability
70%
Legal status
US: RX Only
Chemical Name
Entecavir
Elimination half-life
128–149 hours
Dosage (Strength)
o.5mg, 1mg
Pregnancy
Consult Doctor
Brands
Baraclude
Protein binding
13%
PubChem CID
135398508
MedlinePlus
a605028
ChEBI
473990
ATC code
J05AF10
DrugBank
DB00442
KEGG
D04008
Routes of administration
By mouth (tablets)
Directions
Take Baraclude exactly as prescribed by your healthcare provider. Do not stop abruptly without discussing it with your doctor first. Doing so may cause an acute hepatitis B infection and drug resistance.
Ingredients
The active ingredient in Baraclude generic is entecavir.
Interactions
The known drug-drug interactions with this medication include:
- Cladribine
- Orlistat
Tell your doctor about all medications you are taking before you start Baraclude.
Cautions
Tell your doctor if you have a history of kidney disease before starting Baraclude.
Do not use this medication if you have a hypersensitivity to polysorbate 80 (tweens).
You should get testing for HIV infection before starting Baraclude. Taking it with non-diagnosed HIV may lead to drug resistance.
Your doctor should monitor your liver function while you are taking this medication.
Ask your pharmacist or doctor about all precautions that may apply to you.
Side Effects
Tell your healthcare team about any potential side effects after you start this medication. Common side effects may include:
- Abdominal pain
- Alopecia
- Diarrhea
- Dizziness
- Drowsiness
- Dyspepsia
- Elevated lipase
- Fatigue
- Glycosuria
- Headache
- Hematuria
- Hepatocellular neoplasm
- Hyperglycemia
- Increased kidney enzymes
- Increased liver enzymes
- Insomnia
- Lactic acidosis
- Macular edema
- Malignant neoplasm
- Non immune anaphylaxis
- Skin rash
- Thrombocytopenia
- Vomiting
Buy Baraclude online at Canada Pharmacy with a valid prescription from your doctor.
References
Baraclude [package insert]. Princeton, NJ: Bristol-Myers Squibb; 2015.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 10793
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