What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Bevespi Aerosphere (Glycopyrrolate/Formoterol fumarte)
Generic Equivalent - Bevespi Aerosphere (Glycopyrrolate/Formoterol fumarte)
Prescription Required
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Product Details
Description
Bevespi Aerosphere Inhalation Aerosol is a combination medication containing an anticholinergic, glycopyrrolate, a long-acting beta2-adrenergic agonist (LABA), and formoterol fumarate.
Bevespi Aerosphere is used as maintenance treatment for chronic obstructive pulmonary disease (COPD).
Fact Table
Formula
C19H28BrNO3
License
US DailyMed, EU EMA
Bioavailability
40%
Legal status
RX-only
Chemical Name
Glycopyrrolate/Formoterol fumarte
Elimination half-life
0.6–1.2 hours
Dosage (Strength)
10.7g of 7.2mcg / 5mcg (120 doses / inhaler), 10.7g of 9mcg/4.8mcg (120doses/inhaler)Geberic
Pregnancy
Consult Doctor
Brands
Bevespi Aerosphere
Protein binding
38% to 41%
PubChem CID
3494
MedlinePlus
a602014
ChEBI
90972
ATC code
A03AB02
DrugBank
DBSALT001183
KEGG
D00540
Routes of administration
inhalation
Directions
Bevespi Aerosphere is available as a pressurized metered dose inhaler for inhalation by mouth. Follow the instructions that come with your prescription.
The dose for maintenance treatment of COPD is 2 puffs by mouth twice daily.
Each puff delivers 9 mcg glycopyrrolate and 4.8 mcg of formoterol fumarate.
Ingredients
The active ingredients in Bevespi Aerosphere are micronized glycopyrrolate and micronized formoterol fumarate.
Contraindications
Do not use a LABA without an inhaled corticosteroid if you have asthma.
Discuss your allergies with your doctor. Do not use Bevespi Aerosphere if you are allergic to any of its ingredients.
Cautions
- Talk to your doctor about all the prescription and over-the-counter medications you take, including vitamins and herbal supplements.
- Do not use Bevespi Aerosphere as a rescue inhaler.
- Using Bevespi Aerosphere with other medications that contain a LABA can increase your risk for overdose.
- Seek medical attention immediately if you develop worsening breathing problems, need to use your rescue inhaler more frequently, or your rescue inhaler doesn't fully relieve your symptoms.
- Seek medical attention immediately if you develop sudden breathing trouble after using Bevespi Aerosphere.
- Tell your doctor if you have heart problems or high blood pressure. Contact your doctor right away if you experience a fast or irregular heartbeat, blood pressure problems, or chest pain during treatment with Bevespi Aerosphere.
- Tell your doctor if you have glaucoma or other eye problems. Contact your doctor right away if you experience eye pain, vision problems, nausea, vomiting, or eye redness during treatment with Bevespi Aerosphere.
- Tell your doctor if you have prostatic hyperplasia or bladder-neck obstruction. Contact your doctor right away if you experience trouble urinating, pain when urinating, frequent urination, or urinating in weak streams or drips during treatment with Bevespi Aerosphere.
- Bevespi Aerosphere can cause:
- low potassium levels in the blood: muscle cramps, muscle twitches, irregular heartbeat
- high blood sugar
- Tell your doctor if you have convulsive disorders, thyroid problems, diabetes, or ketoacidosis.
- Tell your doctor if you are pregnant or plan to become pregnant.
- Tell your doctor if you are breastfeeding or plan to breastfeed.
Side Effects
Common side effects of Bevespi Aerosphere include cough and urinary tract infection. Tell your doctor right away if you develop side effects that are bothersome or persistent.
References:
- Bevespi Aerosphere Prescribing Information. Wilmington, DE: AstraZeneca Pharmaceuticals LP; 2019.
- Bevespi Aerosphere (glycopyrrolate and formoterol fumarate). Important Safety Information. https://www.bevespi.com. Accessed January 26, 2022.
- Low Potassium Levels in Your Blood (Hypokalemia). Cleveland Clinic. Last reviewed March 12, 2018. Accessed January 31, 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13573
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