What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Biltricide (Praziquantel)
Prescription Required
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Product Details
Description
Biltricide is a prescription antihelminthic drug used to treat blood fluke infection. Blood flukes are a type of parasite. Blood flukes are not found in the United States, but infection is common in other parts of the world.
Symptoms of schistosomiasis include fever, cough, diarrhea, muscle pain, stomach pain, and rash.
Biltricide paralyzes blood flukes, causing them to detach from blood vessels. Once detached, they can be removed by the immune system.
Fact Table
Formula
C19H24N2O2
License
US FDA
Bioavailability
Relatively small
Legal status
Rx-only
Chemical Name
Praziquantel
Elimination half-life
0.8–1.5 hours
Dosage (Strength)
600mg
Pregnancy
Consult Doctor
Brands
Biltricide
Protein binding
80%
PubChem CID
4891
MedlinePlus
a608048
ChEBI
45267
ATC code
P02BA01
DrugBank
DB01058
KEGG
D00471
Routes of administration
By mouth
Directions
Biltricide dosing is based on weight and type of infection. Your healthcare provider will determine the best dose for you.
Do not take Biltricide in a different way than prescribed. Do not stop Biltricide before finishing the entire course.
Ingredients
The active ingredient in Biltricide is praziquantel.
Interactions
Tell your doctor and pharmacist about all drugs you are taking before starting Biltricide. There are many drug interactions, including:
- Apalutamide
- Atazanavir
- Carbamazepine
- Ceritinib
- Chloroquine
- Cimetidine
- Clarithromycin
- Clofazimine
- Cobicistat and cobicistat-containing coformulations
- Darunavir
- Enzalutamide
- Erdafitinib
- Fexinidazole
- Fosphenytoin
- Fusidic Acid
- Grapefruit Juice
- Idelalisib
- Indinavir
- Itraconazole
- Ivosidenib
- Ketoconazole
- Levoketoconazole
- Lonafarnib
- Lopinavir
- Lumacaftor
- Lumacaftor-ivacaftor
- Mifepristone
- Mitotane
- Nefazodone
- Nelfinavir
- Ombitasvir-paritaprevir-ritonavir
- Ombitasvir-paritaprevir-ritonavir plus dasabuvir
- Phenobarbital
- Phenytoin
- Posaconazole
- Primidone
- Rifampin (rifampicin)
- Ritonavir and ritonavir-containing coformulations
- Saquinavir
- Telithromycin
- Tucatinib
- Voriconazole
Cautions
Tell your healthcare provider if you have a history of heart problems, seizures, or liver disease before starting this medication.
Do not drive a car or operate heavy machinery on the day of treatment or the day after treatment.
Side Effects
The most common side effects of this drug may include:
- Abdominal distress
- Abdominal pain
- Anorexia
- Atrioventricular block
- Bloody diarrhea
- Bradycardia
- Cardiac arrhythmia
- Dizziness
- Drowsiness
- Ectopic beats
- Eosinophilia
- Fatigue
- Fever
- Headache
- Hypersensitivity
- Hypersensitivity reaction
- Increased liver enzymes
- Malaise
- Myalgia
- Nausea
- Paradoxical reaction
- Polyserositis
- Pruritus
- Seizure
- Serum sickness
- Skin rash
- Urticaria
- Ventricular fibrillation
- Vertigo
- Vomiting
- Weakness
References
Biltricide [package insert]. Whitehouse Station, NJ: Bayer HealthCare Pharmaceuticals Inc.; 2010.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12592
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