A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Binosto (Alendronate Sodium)
Brand
Binosto (Alendronate Sodium)
Prescription Required
Strength
Qty
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Your doctor may prescribe Binosto to treat osteoporosis in postmenopausal women or increase bone mass in men with osteoporosis.
Binosto works in cells of the bone called osteoclasts. Under normal conditions, osteoclasts are always breaking down bone, and osteoblasts rebuild bone. In adults with osteoporosis, Binosto attaches to osteoclasts and prevents them from breaking down bone. Binosto incorporated into the matrix of the bone, causing an increase in bone mass over time.
Fact Table
Formula
C4H13NO7P2
License
US FDA, EU EMA
Bioavailability
0.6%
Legal status
Rx-only
Chemical Name
Alendronic acid
Elimination half-life
126 months
Dosage (Strength)
70mg
Pregnancy
Not Recommended
Brands
Fosamax, Binosto
Protein binding
78%
PubChem CID
2088
MedlinePlus
a601011
ChEBI
2567
ATC code
M05BA04
DrugBank
DB00630
KEGG
D07119
Routes of administration
By mouth
Directions
Binosto is available in 70 mg effervescent tablets. Dissolve one Binosto 70 mg tablet in 4 oz of room temperature water and drink it once weekly. Wait five minutes for the tablets to dissolve, and then stir the solution for 10 seconds and consume the content.
Ingredients
The active ingredient in Binosto is alendronate sodium.
Interactions
Tell your doctor and pharmacist about all medications you are taking, including prescription, over-the-counter (OTC), herbals, and supplements.
Common drug-drug interactions with Binosto may include:
Aminoglycosides
Aspirin
Ibuprofen
Naproxen
Parathyroid hormone
Proton pump inhibitors
Cautions
Tell your doctor if you have any abnormalities of the esophagus or cannot stand or sit upright for 30 minutes after taking this medication.
Use caution if you have a history of low calcium in the blood.
Do not use Binosto if you have a dietary sodium restriction.
Do not eat for 30 minutes after taking Binosto.
Do not lie down for 30 minutes after taking Binosto.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13281
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Prescription Required
