What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Binosto (Alendronate Sodium)

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Brand

Binosto (Alendronate Sodium)

Prescription Required

Strength
Qty
70mg

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  • Product Details

    Description

    Your doctor may prescribe Binosto to treat osteoporosis in postmenopausal women or increase bone mass in men with osteoporosis.

    Binosto works in cells of the bone called osteoclasts. Under normal conditions, osteoclasts are always breaking down bone, and osteoblasts rebuild bone. In adults with osteoporosis, Binosto attaches to osteoclasts and prevents them from breaking down bone. Binosto incorporated into the matrix of the bone, causing an increase in bone mass over time.

    Fact Table

    Formula

    C4H13NO7P2

    License

    US FDA, EU EMA

    Bioavailability

    0.6%

    Legal status

    Rx-only

    Chemical Name

    Alendronic acid

    Elimination half-life

    126 months

    Dosage (Strength)

    70mg

    Pregnancy

    Not Recommended

    Brands

    Fosamax, Binosto

    Protein binding

    78%

    PubChem CID

    2088

    MedlinePlus

    a601011

    ChEBI

    2567

    ATC code

    M05BA04

    DrugBank

    DB00630

    KEGG

    D07119

    Routes of administration

    By mouth

    Directions

    Binosto is available in 70 mg effervescent tablets. Dissolve one Binosto 70 mg tablet in 4 oz of room temperature water and drink it once weekly. Wait five minutes for the tablets to dissolve, and then stir the solution for 10 seconds and consume the content.

    Ingredients

    The active ingredient in Binosto is alendronate sodium.

    Interactions

    Tell your doctor and pharmacist about all medications you are taking, including prescription, over-the-counter (OTC), herbals, and supplements.

    Common drug-drug interactions with Binosto may include:

    • Aminoglycosides
    • Aspirin
    • Ibuprofen
    • Naproxen
    • Parathyroid hormone
    • Proton pump inhibitors

    Cautions

    Tell your doctor if you have any abnormalities of the esophagus or cannot stand or sit upright for 30 minutes after taking this medication.

    Use caution if you have a history of low calcium in the blood.

    Do not use Binosto if you have a dietary sodium restriction.

    Do not eat for 30 minutes after taking Binosto.

    Do not lie down for 30 minutes after taking Binosto.

    Side Effects

    Common side effects of Binosto may include:

    • Abdominal pain
    • Acid regurgitation
    • Atypical femur fractures
    • Constipation
    • Decreased serum phosphate
    • Diarrhea
    • Dyspepsia
    • Headache
    • Hypocalcemia
    • Musculoskeletal pain
    • Nausea
    • Osteonecrosis of the jaw

    References

    Binosto [package insert]. San Antonio, TX: Mission Pharmacal; 1995.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13281

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