What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Brisdelle (Paroxetine)


Brisdelle (Paroxetine)

Prescription Required


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Generic Equivalent - Brisdelle (Paroxetine)

Prescription Required


You'll have option to make 4 interest-free payments by credit card once your order is confirmed using Sezzle

  • Product Details


    Brisdelle (paroxetine) is a drug used to treat moderate to severe hot flashes in women with menopause.

    Fact Table




    US FDA, US DailyMed


    about 50%

    Legal status


    Chemical Name


    Elimination half-life

    21 hours

    Dosage (Strength)



    not recommended



    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth


    Brisdelle is available in 7.5 mg capsules.

    The recommended dose is 7.5 mg by mouth once daily at bedtime.


    The active ingredient in Brisdelle is paroxetine. 


    Do not take Brisdelle with monoamine oxidase inhibitors or within 14 days of using a monoamine oxidase inhibitor. 

    Do not take Brisdelle with thioridazine.

    Do not take Brisdelle with pimozide.

    Do not take Brisdelle if you are allergic to paroxetine or any other ingredient in Brisdelle.

    Do not take Brisdelle if you are pregnant.



    See full prescribing information for complete boxed warning.

    • Potential for increased risk of suicidal thinking and behavior
    • Monitor for worsening and emergence of suicidal thoughts and behaviors
    • Before you start taking Brisdelle, tell your doctor:
      • About any allergies you have
      • About any medications you take, including prescription, over-the-counter, vitamins, and herbal supplements
      • About any medical conditions you have
      • If you are pregnant or plan to become pregnant
      • If you are currently breastfeeding or plan to breastfeed
    • Brisdelle can increase the risk of suicidal thinking and behavior. Tell your doctor right away if you experience suicidal thoughts, ideations, or behavioral changes.
    • Brisdelle may increase your risk for serotonin syndrome. Seek medical care right away if you experience agitation, restlessness, trouble sleeping, confusion, fast heart rate, high blood pressure, dilated pupils, loss of muscle coordination, muscle twitching or rigidity, excessive sweating, diarrhea, headache, shivering, or goosebumps. 
    • Brisdelle can reduce the effects of Tamoxifen.
    • Your risk for bleeding increases when taking Brisdelle and non-steroidal anti-inflammatory drugs (NSAIDs), aspirin, or other drugs that increase the risk of bleeding. Watch for signs of bleeding such as nosebleeds, bleeding from your gums, or the presence of blood in your stools.
    • Tell your doctor if you have vision problems such as glaucoma.
    • Tell your doctor if you have seizures or a condition that can cause seizures.
    • Brisdelle can cause low sodium levels in the blood. Seek medical care right away if you experience confusion, nausea, vomiting, energy loss, drowsiness, mood changes, restlessness, muscle weakness, muscle spasms or cramps, or seizures.
    • Brisdelle can increase your risk for bone fractures.
    • Brisdelle can cause mania or hypomania.
    • Brisdelle can cause feelings of restlessness. 
    • Brisdelle can cause problems with sex.
    • Do not drive or operate machinery until you know how Brisdelle affects you.

    Side Effects

    The most common side effects associated with Brisdelle include headache, fatigue, nausea, and vomiting. Contact your doctor right away if you develop side effects that worsen or won't go away.


    1. Brisdelle Prescribing Information. Roswell, GA: Sebela Pharmaceuticals, Inc.; 2021. 
    2. Serotonin syndrome. Mayo Clinic. January 22, 2022. Accessed February 4, 2022. 
    3. Hyponatremia. Mayo Clinic. May 23, 2020. Accessed February 4, 2022.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13596

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