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Broadline (Fipronil / (S)-methoprene / Eprinomectin / Praziquantel)

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A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

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  • Product Details

    Description

    Broadline is a comprehensive topical parasiticide specifically formulated for cats, providing broad-spectrum protection against both external and internal parasites. It combines active ingredients to target fleas, ticks, gastrointestinal worms (including roundworms and tapeworms), and bladder worms, as well as preventing heartworm disease. Broadline is administered as a spot-on treatment, offering a convenient, stress-free solution for cats and kittens from 8 weeks of age and weighing at least 0.8 kg.

    Fact Table

    Formula

    Combination: Fipronil + (S)-Methoprene + Eprinomectin + Praziquantel

    License

    EMA, national veterinary authorities

    Bioavailability

    Topical; systemic absorption of some components

    Legal status

    Veterinary Rx-only (most regions)

    Chemical Name

    Fipronil + (S)-Methoprene + Eprinomectin + Praziquantel

    Elimination half-life

    Fipronil: ~154 hrs; Eprinomectin: ~110 hrs (varies by compound)

    Dosage (Strength)

    Per 0.3–0.9 mL pipette (weight-based dosing)

    Pregnancy

    Not recommended; safety not fully established

    Brands

    Broadline (by Boehringer Ingelheim)

    Protein binding

    High for fipronil and eprinomectin

    PubChem CID

    Fipronil: 60700; Methoprene: 3037356; Eprinomectin: 9832910; Praziquantel: 4891

    MedlinePlus

    Not applicable (veterinary)

    ChEBI

    Fipronil: CHEBI:51220; Praziquantel: CHEBI:44917

    ATC code

    QP54AA51 (combinations for ectoparasites)

    DrugBank

    Fipronil: DB11178; Praziquantel: DB01058

    KEGG

    Praziquantel: D00456

    Routes of administration

    Topical (spot-on)

    Directions

    Apply Broadline topically to the skin on the back of the neck, directly onto the skin and not the fur. The product should be used according to the cat’s body weight and in accordance with the dosing instructions provided in the package insert. A single pipette delivers the full dose. Use monthly or as advised by a veterinarian to maintain effective parasite control.

    Ingredients

    Broadline contains the following active ingredients per 0.9 mL pipette (for cats 2.5–7.5 kg):

    • Fipronil 74.7 mg
    • (S)-Methoprene 90.0 mg
    • Eprinomectin 3.0 mg
    • Praziquantel 24.9 mg

    These ingredients work synergistically to provide endo- and ectoparasiticidal activity.

    Contraindications

    Broadline should not be used in cats weighing less than 0.8 kg or younger than 8 weeks of age. Do not use in animals with known hypersensitivity to any of the active substances or excipients.

    Cautions

    Avoid contact with the cat’s eyes and mouth during application. Ensure treated animals cannot lick the application site until dry. Other animals in the household should be prevented from grooming the treated cat for a short period after application. Wash hands after handling the product. Consult a veterinarian before use in pregnant or lactating cats, or if the cat is concurrently on other medications.

    Side Effects

    Side effects are rare but may include:

    • Temporary alopecia or mild irritation at the application site
    • Salivation, vomiting, or transient behavioral changes if ingested
    • Hypersalivation due to grooming the application area
    • In very rare cases, neurological signs such as ataxia or tremors

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 13184

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