What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Cambia (Diclofenac Potassium)
Prescription Required
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Product Details
Description
Cambia (diclofenac potassium) is used to treat migraines in adults who are at least 18 years old.
Cambia is classified as a non-steroidal anti-inflammatory drug (NSAID).
Cambia should not be used to prevent migraines.
It is unknown whether or not Cambia is a safe and effective treatment for cluster headaches.
Fact Table
Formula
C14H11Cl2NO2
License
US DailyMed
Bioavailability
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Legal status
US: Rx-only / OTC
Chemical Name
Diclofenac
Elimination half-life
1.2–2 h
Dosage (Strength)
50mg
Pregnancy
Not recommended
Brands
Cambia, Cataflam
Protein binding
More than 99%
PubChem CID
3033
MedlinePlus
a689002
ChEBI
47381
ATC code
D11AX18
DrugBank
DB00586
KEGG
D07816
Routes of administration
By mouth
Directions
The instructions that come with your Cambia prescription should be followed. Any questions or concerns you may have can be referred to your doctor or pharmacist.
Cambia dosage:
Cambia is available in 50 mg single-dose packets. Each packet contains a soluble powder that should be mixed with 1 to 2 ounces of water and taken by mouth. The lowest dose that relieves the migraine should be used for the shortest amount of time that is consistent with treatment goals.
Ingredients
Cambia contains diclofenac potassium. Inactive ingredients include anise and mint for flavoring, glycerol behenate, mannitol, potassium bicarbonate, and sucralose.
Contraindications
Do not take Cambia if you are allergic to NSAIDs, diclofenac, or any of the other ingredients contained in Cambia.
Do not take Cambia if you have ever had asthma, hives, or any other type of allergic reaction after aspirin or NSAID use.
Cambia should be avoided with coronary artery bypass graft (CABG) surgery.
Cautions
WARNING: RISK OF SERIOUS CARDIOVASCULAR AND GASTROINTESTINAL EVENTS
See full prescribing information for complete boxed warning
Non-steroidal anti-inflammatory drugs (NSAIDs) cause an increased risk of serious cardiovascular thrombotic events, including myocardial infarction and stroke, which can be fatal. This risk may occur early in treatment and may increase with duration of use
CAMBIA is contraindicated in the setting of coronary artery bypass graft (CABG) surgery
NSAIDs cause an increased risk of serious gastrointestinal (GI) adverse events including bleeding, ulceration, and perforation of the stomach or intestines, which can be fatal. These events can occur at any time during use and without warning symptoms. Elderly patients and patients with a prior history of peptic ulcer disease and/or GI bleeding are at greater risk for serious GI events
- Before you start taking Cambia for your migraines, inform your doctor of:
- All the prescription and over-the-counter medications you take, including vitamins and supplements
- Cambia can interact with other medications that also increase the risk of bleeding including warfarin, aspirin, selective serotonin reuptake inhibitors, and serotonin-norepinephrine reuptake inhibitors
- Cambia can interact with certain other blood pressure medications, causing kidney problems
- Cambia can interact with certain fluid pills
- Cambia can increase digoxin levels
- Your allergies
- Your health problems
- Your pregnancy or breastfeeding status and plans
- Prolonged use of NSAIDs like Cambia can increase the risk for a heart attack, stroke, or other cardiovascular thrombotic events.
- Taking NSAIDs like Cambia can cause severe inflammation, bleeding, ulceration, or perforation of the esophagus, stomach, or intestines. These effects can be life threatening.
- Cambia can cause liver damage.
- Cambia can cause high blood pressure or worsen existing high blood pressure. Check your blood pressure regularly.
- Cambia can worsen heart failure and swelling.
- Cambia can cause kidney damage.
- Cambia can cause increased potassium levels.
- Cambia can cause severe allergic reactions. Seek emergency care immediately if you have shortness of breath, swelling of your face, lips, tongue, or throat, rash, itching, or rapid heart rate.
- Cambia can worsen asthma in patients who have aspirin-sensitive asthma.
- Cambia can cause severe skin reactions. Seek emergency care if you develop a rash, itching, or other signs of a skin reaction.
- Taking too much Cambia can cause headaches.
- Cambia can harm an unborn baby and should not be taken starting at 30 weeks gestation.
- Cambia can cause anemia.
- Cambia reduces inflammation and pain, which can mask a fever and other signs used to diagnose infections.
Side Effects
Nausea and dizziness are common side effects of Cambia; however, these are not all the side effects that may occur with Cambia use. Monitor for side effects and contact your doctor if you develop bothersome or persistent side effects.
Reference:
Cambia (diclofenac potassium), for oral solution. Newark, CA: Depomed. Inc.; 2017.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13245
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