What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Cardizem (Diltiazem)

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Generic

What is a Generic?

Generic Equivalent - Cardizem (Diltiazem)

Prescription Required

Strength
Qty
30mg
60mg
90mg
120mg

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  • Product Details

    Description

    Cardizem (diltiazem hydrochloride) is a medication used to manage chronic stable chest pain and chest pain due to coronary artery spasm.


    Fact Table

    Formula

    C22H26N2O4S

    License

    US DailyMed

    Bioavailability

    40%

    Legal status

    Rx-Only

    Chemical Name

    Diltiazem

    Elimination half-life

    3–4.5 hours

    Dosage (Strength)

    30mg, 60mg, 90mg, 120mg

    Pregnancy

    Not recommended

    Brands

    Cardizem

    Protein binding

    70-80%

    PubChem CID

    39186

    MedlinePlus

    a684027

    ChEBI

    101278

    ATC code

    C05AE03

    DrugBank

    DB00343

    KEGG

    D07845

    Routes of administration

    By mouth

    Directions

    The instructions that come with your Cardizem prescription should be carefully read and followed. If you have any questions or concerns, talk to your doctor or pharmacist.

    Cardizem is available in 30 mg, 60 mg, 90 mg, and 120 mg tablets that should not be crushed or chewed; they should be swallowed whole.

    The typical starting dose is 30 mg by mouth four times a day, before meals and at bedtime. 

    The dosage may be adjusted depending on how well you tolerate the medication. 

    Ingredients

    Each Cardizem tablet contains diltiazem, a calcium ion cellular influx inhibitor. 

    Contraindications

    Do not take Cardizem if you have sick sinus syndrome unless you have a functioning ventricular pacemaker.

    Do not take Cardizem if you have a second- or third-degree AV block unless you have a functioning ventricular pacemaker.

    Do not take Cardizem if you have a systolic blood pressure that is less than 90 mm HG. 

    Do not take Cardizem if you are allergic to diltiazem or any of its other ingredients.

    Do not take Cardizem if you have a heart attack and pulmonary congestion documented on X-ray when admitted to the hospital.

    Cautions

    • Before you start taking Cardizem, inform your doctor of:
      • All the medications you take, including all prescription and over-the-counter medications, herbal supplements, and vitamins
      • Your allergies
      • Your health conditions and medical history
      • Your pregnancy or breastfeeding status
    • Taking Cardizem with beta-blockers or digitalis may affect cardiac conduction. Ask your doctor if you are unsure whether or not you take beta-blockers or digitalis.
    • There is limited experience regarding the use of Cardizem by itself or with beta-blockers in patients who have impaired ventricular function. 
    • Cardizem can cause symptomatic low blood pressure.
    • Cardizem can cause sudden liver damage, although rare and reversible when Cardizem is stopped.

    Side Effects

    Cardizem (diltiazem) side effects include swelling, headache, nausea, dizziness, rash, and lack of energy; however, these may not be all the possible side effects of Cardizem. It's recommended to contact your doctor right away if you develop side effects that bother you or will not resolve.

    Reference:

    Cardizem (diltiazem hydrochloride). Bridgewater, NJ: Valeant Pharmaceuticals North America LLC; 2014.


    Dr Savannah Muncy
    About Dr. Savannah Muncy (Page Author)


    Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 10082

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