What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Cleocin (Clindamycin)
Also Known as Dalacin C
Prescription Required
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Product Details
Description
Cleocin (clindamycin) is used to treat certain bacterial infections of the respiratory tract, skin, blood, intra-abdominal, pelvis, and genital tract.
Cleocin is available in 75 mg, 150 mg, and 300 mg oral capsules.
Fact Table
Formula
C18H33ClN2O5S
License
US FDA
Bioavailability
4–5% (topical)
Legal status
Rx-Only
Chemical Name
Clindamycin
Elimination half-life
2–3 hours
Dosage (Strength)
Cream 2%
Pregnancy
safe
Brands
Cleocin
Protein binding
95%
PubChem CID
446598
MedlinePlus
a682399
ChEBI
3745
ATC code
J01FF01
DrugBank
DB01190
KEGG
D00277
Routes of administration
Topical
Directions
Read the information that comes with your prescription and take Cleocin as your doctor has prescribed. Be sure to finish your course of antibiotics, even if you begin to feel better. If you have any questions or concerns, talk to your doctor or pharmacist.
Dosing:
Serious infections in adults: 150 mg to 300 mg by mouth every 6 hours. If the infection is more severe, the dose may be 300 mg to 450 mg by mouth every 6 hours.
Serious infections in pediatric patients: 8 mg-16 mg/kg/day divided into three or four equal doses. If the infection is more severe, the dose may be 16 mg-20 mg/kg/day divided into three or four equal doses.
Cleocin should be swallowed whole and taken with a full glass of water.
Depending on the infection being treated, treatment may continue up to 10 days.
Ingredients
The active ingredient in each Cleocin capsule is the antibiotic clindamycin. The 75 mg and 150 mg capsules also contain corn starch, FD and C blue no. 1, FD and C yellow no.5, gelatin, lactose, magnesium stearate, and talc. Titanium dioxide is also contained in the 150 mg capsules. The 300 mg capsules contain corn starch, FD and C blue no. 1, gelatin, lactose, magnesium stearate, talc, and titanium dioxide.
Contraindications
Do not take Cleocin if you have an allergy to it or lincomycin.
Cautions
Cleocin has FDA Boxed Warnings regarding the risk of mild diarrhea to fatal colitis and overgrowth of Clostridium difficile (C. diff).
- Before you start taking Cleocin for your bacterial infection, be sure to inform your doctor:
- Of any medications you take
- Your allergies
- Your health history and medical problems
- If you are pregnant or breastfeeding
- Cleocin should not be used to treat meningitis.
- Cleocin can cause kidney damage.
- Cleocin can cause serious allergic reactions. Seek emergency care immediately if you have trouble breathing; swelling of your face, lips, or tongue; or skin reactions.
Side Effects
Cleocin can have side effects such as nausea, vomiting, and diarrhea. It can also cause serious side effects like C. diff, skin rashes, kidney damage, and lab abnormalities. Contact your doctor immediately if you have troublesome or persistent side effects.
Reference:
- Cleocin (clindamycin hydrochloride). New York, NY: Pharmacia & Upjohn Company LLC; 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 10088
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