What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Combivent Respimat Inhaler (Ipratropium / Albuterol)
Prescription Required
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Product Details
Description
Combivent Respimat Inhalation Spray contains an anticholinergic, ipratropium bromide, and a beta2-adrenergic agonist, albuterol sulfate, to treat chronic obstructive pulmonary disease (COPD) in patients who need a second medication to help open up their airways for easier breathing.
Combivent Respimat comes as an inhaler that delivers 20 mcg of ipratropium bromide and 100 mcg of albuterol per spray.
Fact Table
Formula
C46H74BrN3O13S
License
US DailyMed
Bioavailability
2% and 7 to 28%
Legal status
Rx-Only
Chemical Name
Ipratropium bromide/salbutamol
Elimination half-life
2 hours
Dosage (Strength)
20/100 mcg (120 doses/inhaler)
Pregnancy
Consult Doctor
Brands
Combivent Respimat
Protein binding
Less than 20%
PubChem CID
24847804
MedlinePlus
a601063
ChEBI
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ATC code
R03AK04
DrugBank
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KEGG
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Routes of administration
Inhalation
Directions
Carefully read and follow the instructions that come with your prescription. Use Combivent Respimat as your doctor has prescribed. Let your doctor or pharmacist know if you have any questions or concerns.
The recommended dose is to inhale one spray four times a day. Do not exceed six inhalations within 24 hours.
Ingredients
Ipratropium bromide and albuterol sulfate are the active ingredients contained in Combivent Respimat.
Contraindications
Do not use Combivent Respimat if you are allergic to any of its ingredients.
Do not use Combivent Respimat if you are allergic to atropine or any of its derivatives.
Cautions
- Before you treat your COPD with Combivent Respimat, tell your doctor about:
- About all the medications you take
- Your allergies
- Your health history and medical problems
- Your pregnancy or breastfeeding status
- Combivent Respimat can cause life threatening airway constriction. Seek emergency care immediately if this occurs.
- Beta2-adrenergic agonists, which is a component of Combivent Respimat, can cause serious cardiovascular effects such as high blood pressure, heart attack, rapid heart rate, and other heart arrhythmias. Caution should be used in patients with disorders of the cardiovascular system.
- Ipratropium bromide, a component of Combivent Respimat, can cause increased pressure in the eyes and should be used with caution in patients with glaucoma.
- Ipratropium bromide, a component of Combivent Respimat, can cause urinary retention and should be used with caution in patients who have prostate problems or bladder-neck obstructions.
- Combivent Respimat can cause allergic reactions that can become severe. Seek emergency care immediately if you have trouble breathing, swelling of the face, lips, or tongue, or skin rash.
- Because Combivent Respimat contains albuterol, it should be used cautiously in patients who have seizures, high thyroid levels, diabetes, and in patients who are sensitive to sympathomimetic amines.
- Beta2-adrenergic agonists, which is a component of Combivent Respimat, can cause low potassium levels in the blood.
Side Effects
Combivent Respimat side effects include cough, shortness of breath, headache, bronchitis, nasopharyngitis, and upper respiratory tract infections. These are not all the side effects that can occur. Contact your doctor right away if you develop side effects that worry you or won't go away.
Reference:
- Combivent Respimat (ipratropium bromide and albuterol inhalation spray), for oral inhalation use. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12634
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