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Combivent Respimat Inhaler (Ipratropium / Albuterol)
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Product Details
Description
Combivent Respimat Inhalation Spray contains an anticholinergic, ipratropium bromide, and a beta2-adrenergic agonist, albuterol sulfate, to treat chronic obstructive pulmonary disease (COPD) in patients who need a second medication to help open up their airways for easier breathing.
Combivent Respimat comes as an inhaler that delivers 20 mcg of ipratropium bromide and 100 mcg of albuterol per spray.
Fact Table
Formula
C46H74BrN3O13S
License
US DailyMed
Bioavailability
2% and 7 to 28%
Legal status
Rx-Only
Chemical Name
Ipratropium bromide/salbutamol
Elimination half-life
2 hours
Dosage (Strength)
20/100 mcg (120 doses/inhaler)
Pregnancy
Consult Doctor
Brands
Combivent Respimat
Protein binding
Less than 20%
PubChem CID
24847804
MedlinePlus
a601063
ChEBI
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ATC code
R03AK04
DrugBank
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KEGG
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Routes of administration
Inhalation
Directions
Carefully read and follow the instructions that come with your prescription. Use Combivent Respimat as your doctor has prescribed. Let your doctor or pharmacist know if you have any questions or concerns.
The recommended dose is to inhale one spray four times a day. Do not exceed six inhalations within 24 hours.
Ingredients
Ipratropium bromide and albuterol sulfate are the active ingredients contained in Combivent Respimat.
Contraindications
Do not use Combivent Respimat if you are allergic to any of its ingredients.
Do not use Combivent Respimat if you are allergic to atropine or any of its derivatives.
Cautions
- Before you treat your COPD with Combivent Respimat, tell your doctor about:
- About all the medications you take
- Your allergies
- Your health history and medical problems
- Your pregnancy or breastfeeding status
- Combivent Respimat can cause life threatening airway constriction. Seek emergency care immediately if this occurs.
- Beta2-adrenergic agonists, which is a component of Combivent Respimat, can cause serious cardiovascular effects such as high blood pressure, heart attack, rapid heart rate, and other heart arrhythmias. Caution should be used in patients with disorders of the cardiovascular system.
- Ipratropium bromide, a component of Combivent Respimat, can cause increased pressure in the eyes and should be used with caution in patients with glaucoma.
- Ipratropium bromide, a component of Combivent Respimat, can cause urinary retention and should be used with caution in patients who have prostate problems or bladder-neck obstructions.
- Combivent Respimat can cause allergic reactions that can become severe. Seek emergency care immediately if you have trouble breathing, swelling of the face, lips, or tongue, or skin rash.
- Because Combivent Respimat contains albuterol, it should be used cautiously in patients who have seizures, high thyroid levels, diabetes, and in patients who are sensitive to sympathomimetic amines.
- Beta2-adrenergic agonists, which is a component of Combivent Respimat, can cause low potassium levels in the blood.
Side Effects
Combivent Respimat side effects include cough, shortness of breath, headache, bronchitis, nasopharyngitis, and upper respiratory tract infections. These are not all the side effects that can occur. Contact your doctor right away if you develop side effects that worry you or won't go away.
Reference:
- Combivent Respimat (ipratropium bromide and albuterol inhalation spray), for oral inhalation use. Ridgefield, CT: Boehringer Ingelheim Pharmaceuticals, Inc.; 2021.
Frequently Asked Questions about Combivent Respimat Inhaler (Ipratropium / Albuterol)
What is COMBIVENT RESPIMAT inhaler used for?
Combivent Respimat treats ongoing lung disease symptoms like wheezing and shortness of breath caused by COPD, which includes bronchitis and emphysema. It contains ipratropium and albuterol, which relax muscles around the airways to ease breathing.
How to use COMBIVENT RESPIMAT inhaler?
Combivent Respimat is usually used 4 times per day. Follow your doctor’s dosing instructions very carefully. Do not use more than 6 inhalations in a 24-hour period. Overuse of Combivent Respimat may increase the risk of death. It is critical that you use only the prescribed dose of this medicine.
How often can you use Combivent inhaler?
Combivent Respimat is usually used 4 times per day. Patients may take additional inhalations as required; however, the total number of inhalations should not exceed six in 24 hours.
Is Combivent a steroid?
No, Combivent Respimat is not a steroid. It contains two medications: ipratropium and albuterol, which help relax and open up the airways in your lungs.
Who should not take Combivent?
Combivent shouldn't be used by those allergic to albuterol, ipratropium, or atropine. People with conditions like heart disease, high blood pressure, epilepsy, diabetes, glaucoma, or kidney issues should talk to their doctor before using it.
How long can you use COMBIVENT RESPIMAT?
Combivent Respimat is usually used 4 times per day. The inhaler will deliver 120 puffs and last 30 days if used at 1 puff four times daily.
How long does it take for Combivent to work?
For many people, Combivent Respimat begins working in 15 minutes.
What are the benefits of Combivent?
Combivent Respimat helps to relax the muscles in your airways so that the airways open up and you can breathe more easily. Controlling symptoms of breathing problems can decrease time lost from work or school.
What happens if you take too much Combivent?
Overuse of Combivent Respimat may increase the risk of death. If you experience narrowing of the airways getting worse (paradoxical bronchospasm) which may be life threatening, stop taking Combivent Respimat at once and call your doctor or get emergency help.
Is Combivent similar to Symbicort?
Both Combivent and Symbicort treat COPD, but they have different ingredients. Combivent mixes an anticholinergic bronchodilator with a selective beta2-adrenergic bronchodilator, while Symbicort blends a corticosteroid with a long-acting bronchodilator.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12634
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