What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Compazine (Prochlorperazine)

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Generic

Generic Equivalent - Compazine (Prochlorperazine)

Prescription Required

Strength
Qty
5mg

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  • Product Details

    Description

    Compazine is a medication commonly prescribed to treat nausea and vomiting but can also be used for migraine treatment. Compazine was initially used as an antipsychotic agent but is no longer used for this purpose.

    Compazine works by blocking dopamine receptors in the brain responsible for feelings of nausea. Compazine blocks the release of hormones that cause nausea and vomiting.

    Directions

    Compazine is available in 5 mg and 10 mg tablets.

    The normal dose of Compazine is 5 to 10 mg by mouth every 3 to 4 hours as needed for nausea and vomiting.

    The maximum dose of Compazine in one day is 40 mg.

    Take Compazine with food or water as tolerated.

    Ingredients

    The active ingredient in Compazine is prochlorperazine, which is also the name of the Compazine generic.

    Interactions

    Common drug-drug interactions with Compazine include:

    • Aclidinium
    • Azelastine
    • Bromperidol
    • Buprenorphine
    • Cabergoline
    • Clozapine
    • Dofetilide
    • Dopamine agonists
    • Flunitrazepam
    • Glycopyrrolate
    • Iohexol
    • Ipratropium
    • Metoclopramide
    • Opioid agonists
    • Orphenadrine
    • Oxybate salt products
    • Potassium chloride
    • Pramlintide
    • Saquinavir
    • Suvorexant
    • Thalidomide
    • Tiotropium
    • Umeclidinium
    • Zolpidem

    Cautions

    Older adults with dementia-related psychosis should not use Compazine because antipsychotic medications have been shown to increase death risk when used for this purpose.

    Use caution if you have a history of heart disease. 

    Compazine should not be used for the long-term treatment of nausea and vomiting. 

    Compazine can cause dizziness or drowsiness. Do not drive until you know how it will affect you.

    Side Effects

    Common adverse reactions to Compazine may include:

    • Agranulocytosis
    • Amenorrhea
    • Blurred vision
    • Dizziness
    • Drowsiness
    • Extrapyramidal reactions
    • Hypotension
    • Leukopenia
    • Neuroleptic malignant syndrome (NMS)
    • Skin reactions


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    References

    Compazine [package insert]. Research Triangle Park, NC: GlaxoSmithKline; 2004.



    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 2691

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