Description
Cordran Tape contains flurandrenolide, a potent topical corticosteroid embedded in a transparent, occlusive plastic surgical tape. It is designed to treat inflammatory and pruritic manifestations of corticosteroid-responsive dermatoses, particularly in areas where standard topical formulations may not adhere well or provide sufficient occlusion. The tape allows for sustained delivery of medication directly to the lesion, enhancing absorption and efficacy while providing a protective barrier.
| F act Table |
| Formula | C24H33FO6 |
| License | US FDA |
| Bioavailability | Topical corticosteroids generally have low systemic bioavailability when used as directed |
| Legal status | Prescription only (Rx) |
| Chemical Name | Flurandrenolide |
| Elimination half-life | Not well established (topical use) |
| Dosage (Strength) | 4 mcg/cm² (in Cordran Tape) |
| Pregnancy | Use with caution; consult physician (Pregnancy Category C) |
| Brands | Cordran Tape, Cordran Cream, Cordran Lotion |
| Protein binding | Moderate (specific value not well documented) |
| PubChem CID | 5878 |
| MedlinePlus | a601068 |
| ChEBI | 31528 |
| ATC code | D07AC02 |
| DrugBank | DB00184 |
| KEGG | D00345 |
| Routes of administration | Topical (tape, cream, ointment, lotion) |
Directions
Apply Cordran Tape directly over the affected area with the medicated side in contact with the skin. Cut the tape to the appropriate size, ensuring it completely covers the lesion. It may be left in place for up to 12 hours and then replaced with a new piece if needed. Treatment duration should be based on clinical response and reassessed periodically. Avoid use under occlusive dressings unless directed by a healthcare provider.
Ingredients
Each square centimeter of Cordran Tape contains 4 mcg of flurandrenolide in a polyethylene film. The tape is also composed of an acrylic ester copolymer adhesive and backing film to ensure flexibility and adherence.
Contraindications
Cordran Tape is contraindicated in patients with known hypersensitivity to flurandrenolide or any component of the formulation. It should not be used in the treatment of viral, fungal, or bacterial skin infections, or in patients with untreated tuberculosis or perioral dermatitis.
Cautions
Long-term use of topical corticosteroids may lead to local adverse effects such as skin atrophy, striae, or telangiectasia, particularly with occlusive application. Use with caution in pediatric patients due to the potential for systemic absorption and hypothalamic-pituitary-adrenal (HPA) axis suppression. Avoid use on the face, groin, or axillae unless directed by a healthcare professional. Do not apply to weeping or exudative lesions, or areas of skin breakdown.
Side Effects
Commonly reported side effects include:
- Burning, itching, or irritation at the application site
- Skin atrophy or striae with prolonged use
- Perioral dermatitis or acneiform eruptions Rare systemic effects may occur with prolonged or extensive use.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 2692
Prescription Required
