What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Crinone Gel 8%


Crinone Gel 8%

Prescription Required

8% x 90g
8% 1.45g applicators

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  • Product Details


    What is Crinone?

    • Crinone (Progesterone) gel is a topical medication used for hormone replacement therapy in assisted reproduction technology or secondary amenorrhea.

    How does it work?

    • Progesterone is a naturally occurring hormone in human females and has a variety of effects on the body. Crinone is applied vaginally and absorbed into the bloodstream to supplement the patient's existing progesterone levels.

    How is it supplied?

    • You can buy Crinone gel online at Canada Pharmacy as an 8% 90gm tube.

    How should I store it?

    • Store your Crinone at room temperature and keep it out of reach of children.

    Fact Table




    US: FDA


    OMP: less than 10%

    Legal status

    RX Only

    Chemical Name


    Elimination half-life

    5-20 minutes

    Dosage (Strength)

    4%, 8%


    Consult a doctor



    Protein binding

    96%-99% bound to serum proteins, primarily to serum albumin (50%-54%) and transcortin (43%-48%)

    PubChem CID






    ATC code






    Routes of administration

    By mouth, topical/transdermal, vaginal, intramuscular injection, subcutaneous injection, subcutaneous implant


    Are there any special instructions?

    • Use your applicator only as instructed by your doctor and the product labeling.
      • Most applicators are intended for single-only.
    • Wash your hands before and after each application of Crinone.

    What is the usual Crinone gel dosage?

    • Assisted Reproductive Technology
      • Apply Crinone 8% vaginally once daily (90mg dose)
        • Your doctor could increase your dose if needed.
      • Secondary Amenorrhea
        • Apply Crinone 4% vaginally every other day for a total of six doses.
          • Your doctor could increase your dose to 8% if needed.


    What is the active ingredient in Crinone?

    • Progesterone

    What are the inactive ingredients?

    • For a complete list of inactive ingredients, click here or check the product packaging.


    • No drug interactions have been assessed with Crinone.


    What is the active ingredient in Crinone?

    • Progesterone

    What are the inactive ingredients?

    • For a complete list of inactive ingredients, click here or check the product packaging.


    • No drug interactions have been assessed with Crinone.

    Side Effects

    Who should avoid taking Crinone?

    • Do not use Crinone if:
      • You have a known allergy to any of the ingredients.
      • You have unusual menstrual bleeding that has not been assessed by a doctor.
      • You have a history of liver disease.
      • Have cancer of the breast or genital tissue.
      • Have had a miscarriage and could still have fetal tissue in the uterus.
      • Have a history of blood clots.

    What are the risks?

    • If you are pregnant, breastfeeding, or considering becoming pregnant, talk to your doctor about the risks of using Crinone.
    • Crinone can cause blood clots that can be fatal. Discuss this risk with your doctor.
    • Progesterone therapy can cause fluid retention. Discuss your risk with your doctor.
    • Progesterone therapy can cause glucose intolerance. Discuss your risk with your doctor.

    What are the potential side effects of Crinone?

    • Blood clots
    • Pulmonary embolism
    • Stroke
    • Abdominal pain
    • Perineal pain
    • Cramps
    • Bloating
    • Headache
    • Fatigue
    • Increased appetite
    • Constipation
    • Diarrhea
    • Nausea
    • Joint pain
    • Depression
    • Mood swings
    • Sleep disorder
    • Nervousness
    • Decreased libido
    • Breast enlargement
    • Excessive urination at night
    • Vaginal discharge
    • Upper respiratory tract infection

    Other Considerations

    • Compare the Canada Pharmacy Crinone gel cost to your local drug store.
    • To share this product page with a friend or relative, have them search "Crinone gel 8 buy online"


    1. DailyMed - CRINONE- PROGESTERONE GEL. (2017). Retrieved May 23, 2020.
    2. Healthline: Secondary Amenorrhea. (2018). Retrieved July 23, 2020.

    Frequently Asked Questions about Crinone Gel

    What is Crinone Gel?

    Crinone Gel is a vaginal gel that contains the hormone progesterone. It is used to supplement or replace natural progesterone in women.

    How is Crinone Gel used?

    Crinone Gel is typically applied directly into the vagina using a pre-filled applicator.

    What are the indications for Crinone Gel?

    Crinone Gel is often prescribed for women undergoing fertility treatments, for women with progesterone deficiency, and sometimes in early pregnancy to support the uterine lining.

    Are there any side effects associated with Crinone Gel?

    Some common side effects include vaginal discharge, vaginal irritation, and bloating. Always consult with a healthcare professional about potential side effects.

    How often should I use Crinone Gel?

    The frequency of use will depend on the specific medical condition and the doctor's prescription. Always follow the recommended dosage.

    Can I use Crinone Gel during pregnancy?

    Crinone Gel is sometimes prescribed during early pregnancy to support the uterine lining. However, always consult with a healthcare professional before using any medication during pregnancy.

    What should I do if I miss a dose?

    If you miss a dose, use it as soon as you remember. If it's close to the time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

    Can I use other vaginal products while using Crinone Gel?

    It is essential to consult with a healthcare professional before using other vaginal products concurrently with Crinone Gel.

    How should I store Crinone Gel?

    Store Crinone Gel at room temperature, away from direct sunlight and moisture.

    Is there a generic version of Crinone Gel available?

    There may be generic versions available, but it's essential to consult with a pharmacist or healthcare provider about the availability and suitability of generic alternatives.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 10027

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