A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Depen (Penicillamine)
Brand
Depen (Penicillamine)
Prescription Required
Strength
Qty
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Wilson disease: abnormally high copper in the body
Depen works by attaching to the substance, and the compound is then excreted in the urine.
Fact Table
Formula
C5H11NO2S
License
US FDA
Bioavailability
Variable
Legal status
Rx-only
Chemical Name
Penicillamine
Elimination half-life
1 hour
Dosage (Strength)
250mg
Pregnancy
Not Recommended
Brands
Depen
Protein binding
50%
PubChem CID
5852
MedlinePlus
a618021
ChEBI
7959
ATC code
M01CC01
DrugBank
DB00859
KEGG
D00496
Routes of administration
By mouth
Directions
Take Depen exactly as prescribed by your doctor. The dosage ranges from 250 mg to 4000 mg per day and is divided into one to four doses.
Take the Depen (penicillamine) dosage on an empty stomach one hour before and two hours after meals.
Ingredients
The active ingredient in Depen is penicillamine.
Interactions
Drug interactions with this medication may include:
Digoxin
Gold sodium thiomalate
Polyvalent cation containing products
Cautions
Depen should only be used under the close supervision of a physician experienced in using it because it has many potential side effects and toxicities.
Quickly report any fever, sore throat, chills, bruising, or bleeding to your doctor if you experience them while taking this medication.
You may need to take pyridoxine (vitamin B6) while taking this medication.
Older adults are more susceptible to taste alterations and skin rash while taking this medication.
Tell your doctor if you have a history of kidney problems.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Prescription Required
