A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Deplin (Levomefolate Calcium)
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Product Details
Description
Deplin is a prescription medical food that is used to increase folate levels in the treatment of Major Depressive Disorder (MDD) or hyperhomocysteinemia in patients with schizophrenia. Deplin is the brand name for folate, which is usually made in the body but can be deficient in some conditions.
Folate is responsible for helping to create DNA, RNA, and other essential molecules in the body. Deplin replaces folate that cannot be absorbed from the diet alone.
Fact Table
Formula
C20H25N7O6
License
US FDA
Bioavailability
-
Legal status
US: OTC
Chemical Name
Levomefolate Calcium
Elimination half-life
3 hour
Dosage (Strength)
7.5mg, 15mg
Pregnancy
Consult Doctor
Brands
Deplin
Protein binding
98%
PubChem CID
444412
MedlinePlus
-
ChEBI
136009
ATC code
B03BB51
DrugBank
DB11256
KEGG
D09353
Routes of administration
Oral
Directions
For depression, the usual dose is one Deplin 15 mg capsule or one to two 7.5 mg capsules once daily in addition to standard antidepressant therapy.
For schizophrenia, the dosage is also 7.5-15 mg by mouth once daily.
Only use Deplin under the supervision of a physician or other healthcare professional. Deplin is a medical food that should only be used by people who cannot obtain the nutrient with normal diet modifications.
Store Deplin at room temperature, protected from heat, light, and moisture.
Ingredients
The active ingredient in Deplin generic is L-methylfolate.
Interactions
Deplin can interact with many other substances, including:
Do not take this medication if you have a known hypersensitivity to Deplin or any of the inactive ingredients.
Side Effects
No significant Deplin side effects have been reported with Deplin except for allergic (hypersensitive reactions).
References
Deplin. Covington, LA: Pamlab; 2009.
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 10252
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