What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Dicloxacillin Generic
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Product Details
Description
Dicloxacillin is a prescription antibiotic that your doctor can prescribe for certain types of infections including skin infections and infections of prosthetic joints. It is typically started in the hospital as an infusion before someone is converted to the oral formulation.
Dicloxacillin is an antibiotic that works by disrupting the formation of bacterial cell walls. Cell walls protect bacteria from the environment, and by blocking the formation of cell walls, the bacteria die, helping to treat the infection.
Fact Table
Formula
C19H17Cl2N3O5S
License
US FDA
Bioavailability
60 to 80%
Legal status
Rx-only
Chemical Name
Dicloxacillin
Elimination half-life
0.7 hours
Dosage (Strength)
250mg, 500mg
Pregnancy
Consult Doctor
Brands
Generic
Protein binding
98%
PubChem CID
18381
MedlinePlus
a685017
ChEBI
4511
ATC code
J01CF01
DrugBank
DB00485
KEGG
D02348
Routes of administration
Oral
Directions
Take dicloxacillin exactly as directed by your doctor. The directions will be different depending on what is being treated.
The usual dosage for prosthetic joint infections is 500 mg three to four times daily for at least three months. Some people may need to continue indefinitely.
The usual dosage for skin infections is 250-500 mg three to four times daily for 5-7 days.
Ingredients
The active ingredient in dicloxacillin is dicloxacillin since it is a generic medication.
Interactions
The most common drug-drug interactions with this drug can include:
- Acemetacin
- Aminoglycosides
- BCG (intravesical)
- BCG vaccine
- Brivaracetam
- CarBAMazepine
- Carisoprodol
- Cholera vaccine
- CloZAPine
- DiazePAM
- Dichlorphenamide
- Etravirine
- Fosphenytoin-Phenytoin
- Hormonal contraceptives
- Immune checkpoint inhibitors
- Lactobacillus and Estriol
- Methotrexate
- Mycophenolate
- Nelfinavir
- NiMODipine
- Omeprazole
- Ospemifene
- Probenecid
- Selpercatinib
- Sirolimus
- Sodium picosulfate
- Tacrolimus
- Tetracyclines
- Typhoid vaccine
- Ubrogepant
- Vitamin K antagonists
- Voriconazole
Tell your doctor and pharmacist if you experience any of the above side effects while taking this drug.
Cautions
Tell your doctor if you have a history of kidney or liver problems before starting this drug.
Side Effects
Dicloxacillin side effects may include:
- Abdominal pain
- Anemia
- Diarrhea
- Eosinophilia
- Fever
- Hematuria
- Hemolytic anemia
- Hepatotoxicity
- Hypersensitivity reaction
- Increased blood urea nitrogen
- Increased liver enzymes
- Increased serum creatinine
- Leukopenia
- Nausea
- Neutropenia
- Prolonged prothrombin time
- Psudomembranous colitis
- Seizure
- Skin rash
- Thrombocytopenia
- Vaginitis
- Vomiting
References
Dicloxacillin. Princeton, NJ: Sandoz, Inc.; 2018.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13599
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