What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Doryx (Doxycycline Hyclate)


Doryx (Doxycycline Hyclate)

Prescription Required


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  • Product Details


    Your doctor may prescribe Doryx for acne or a variety of other infective conditions, including:

    • Respiratory tract infections
    • Sexually transmitted infections
    • Malaria prophylaxis
    • Other bacterial infections that are susceptible to doxycycline

    Doryx is an antibacterial agent that works by preventing the replication of many different types of bacteria. It is not known how this medication works to treat acne, but it is thought that certain types of bacteria may contribute to the development of acne.

    Fact Table




    US FDA



    Legal status

    Rx Only

    Chemical Name


    Elimination half-life

    10–22 hours

    Dosage (Strength)

    50mg, 100mg


    Consult Doctor


    Doxy, Doryx, Vibramycin

    Protein binding


    PubChem CID






    ATC code






    Routes of administration

    By mouth, intravenous


    The standard dosage is 100mg by mouth twice daily on the first day of treatment, followed by 100 mg once daily for as long as directed. For severe acne infections, the dosage may be increased to 100 mg twice daily.

    Swallow the capsule whole with a full glass of water. Painful esophageal ulcers have been reported when the capsule becomes lodged in the throat.


    The active ingredient in Doryx is doxycycline hyclate delayed-release.

    The tablets are available in 80 mg, 100 mg, 150 mg, and 200 mg.


    Common interactions between Doryx and other medications include:

    • Aminolevulinic Acid
    • Antacids
    • Barbiturates
    • BCG
    • Bile Acid Sequestrants
    • Bismuth Subsalicylate
    • Calcium Salts
    • Carbamazepine
    • Cholera Vaccine
    • Fosphenytoin
    • Iron Preparations
    • Lithium
    • Mecamylamine
    • Methoxyflurane
    • Multivitamins
    • Penicillin
    • Proton Pump Inhibitors
    • Quinapril
    • Sucralfate
    • Typhoid Vaccine
    • Warfarin


    Doryx may increase your sensitivity to the sun. Wear appropriate sun protection while using this medication.

    Ask your doctor about all the side effects that apply to you.

    Side Effects

    Common adverse reactions may include:

    • Abdominal distention
    • Abdominal pain
    • Anorexia
    • Bone growth suppression
    • Diarrhea
    • Drug reaction with eosinophilia and systemic symptoms (DRESS)
    • Erythematous rash
    • Erythema multiforme
    • Esophageal injury
    • Increased blood urea nitrogen
    • Increased lactate dehydrogenase
    • Increased serum glucose
    • Photosensitivity
    • Stevens-Johnson syndrome
    • Upper abdominal pain
    • Vulvovaginal candidiasis
    • Xerostomia


    Doryx [package insert]. Rockaway, NJ: Warner Chilcott; 2013.

    Frequently Asked Questions about Doryx (Doxycycline Hyclate)

    What is Doryx (Doxycycline Hyclate)?

    Doryx is a brand name for a medication that contains doxycycline hyclate. It is an antibiotic used to treat various bacterial infections.

    What conditions does Doryx treat?

    Doryx is commonly prescribed to treat infections such as acne, respiratory tract infections, urinary tract infections, Lyme disease, and certain sexually transmitted infections, among others.

    How does Doryx work?

    Doryx works by inhibiting the growth and spread of bacteria in the body. It does this by preventing bacteria from producing the proteins they need to thrive.

    Is Doryx available over the counter?

    No, Doryx is a prescription medication, which means you need a doctor's prescription to obtain it.

    What should I tell my doctor before taking Doryx?

    You should inform your doctor about any allergies you have, other medications you are taking, your medical history (especially if you have liver or kidney disease), and if you are pregnant or breastfeeding. This information helps your doctor determine if Doryx is safe and appropriate for you.

    How should I take Doryx?

    Follow your doctor's instructions carefully. Typically, Doryx is taken with a full glass of water and should be taken with food or milk to minimize stomach upset. Do not crush or break the tablets. Take the prescribed dose at the same time each day.

    What should I do if I miss a dose of Doryx?

    If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for a missed one.

    Are there any side effects associated with Doryx?

    Like all medications, Doryx may cause side effects. Common side effects include nausea, vomiting, diarrhea, and skin sensitivity to sunlight. Contact your doctor if you experience severe or persistent side effects.

    How long should I take Doryx?

    You should take Doryx for the full course prescribed by your doctor, even if you start feeling better before you've finished the medication. Stopping antibiotics too soon may allow the infection to return or worsen.

    Is Doryx effective against viral infections like the common cold or flu?

    No, Doryx is an antibiotic and is only effective against bacterial infections. It will not treat viral infections such as the common cold or flu.

    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 11665

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