Dupixent (Dupilumab)
What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Coming Soon – Save up to 85%
Sign up to get exclusive coupon discounts and be the first to be notified when we have this product available.
Prescription Required
-
Product Details
Description
Dupixent (dupilumab) is a medication that is injected underneath the skin to treat atopic dermatitis, asthma, chronic rhinosinusitis with nasal polyps, eosinophilic esophagitis, and prurigo nodularis.
Dupixent comes in single-dose prefilled syringes with needle shields in the following concentrations:
- 300 mg/2 mL
- 200 mg/1.14 mL
- 100 mg/0.67 mL
Dupixent also comes in single-dose prefilled pens of the following strengths:- 300 mg/2 mL
- 200 mg/1.14 mL
Fact Table
Formula
C6512H10066N1730O2052S46
License
US DailyMed, US FDA
Bioavailability
Dupilumab is administered by injection and does not have a specific bioavailability value since it acts systemically
Legal status
Rx-only
Chemical Name
Dupilumab
Elimination half-life
The elimination half-life of dupilumab is approximately 26 days
Dosage (Strength)
Typically ranging from 150 mg to 300 mg
Pregnancy
Consult Doctor
Brands
Dupixent is the primary brand name for dupilumab
Protein binding
Dupilumab does not significantly bind to plasma proteins
PubChem CID
Not available because this is not a discrete structure
MedlinePlus
a617021
ChEBI
The ChEBI (Chemical Entities of Biological Interest) entry for dupilumab is not available as it is a protein-based drug
ATC code
D11AH05
DrugBank
DB12159
KEGG
D10354
Routes of administration
Dupilumab is administered by subcutaneous injection
Directions
Use Dupixent exactly as instructed by your doctor. If you have any questions or concerns about the medication, talk to your doctor or pharmacist.
Your dose will depend on the condition being treated. Dosing for pediatric patients will also depend on weight.
Your doctor will advise you on how to inject Dupixent, how much medication to inject, and how often you should inject it.
Ingredients
Dupilumab is the active ingredient in Dupixent. Inactive ingredients include L-arginine hydrochloride, L-histidine, polysorbate 80, sodium acetate, sucrose, and water for injection.
Contraindications
Do not take Dupixent if you are allergic to any of its ingredients or excipients.
Cautions
- Before you begin using Dupixent injections, tell your doctor about:
- All the prescription and over-the-counter medications you take
- Your allergies
- Your current health conditions and past medical history
- Your pregnancy or breastfeeding status
- Dupixent may cause hypersensitivity reactions, including anaphylaxis, serum sickness, swelling underneath the skin, hives, rash, tender bumps under the skin, and skin lesions. If any of these reactions occur, seek medical care right away.
- Dupixent can cause eye problems. If you experience eye symptoms, contact your doctor right away.
- If you experience a rash, worsening pulmonary symptoms, and/or nerve pain, contact your doctor right away.
- Do not abruptly stop taking corticosteroids when you start treatment with Dupixent. Steroids should be slowly tapered off.
- If you develop joint problems while taking Dupixent, contact your doctor right away.
- Helminth infections should be treated before starting Dupixent.
- Live vaccines should not be administered while receiving Dupixent.
Side Effects
Dupixent side effects include conjunctivitis, blepharitis, oral herpes, keratitis, itchy eyes, other herpes simplex virus infection, dry eye, eosinophilia, injection site reactions, mouth or throat pain, problems sleeping, toothache, gastritis, joint pain, and upper respiratory tract infections. Other side effects may also occur. Contact your doctor right away if you have worrisome or persistent side effects.
Looking for a competitive Dupixent cost? With a valid prescription from your doctor, you can buy Dupixent injections online at a competitive price from Canada Pharmacy .
Reference:
- Dupixent. Tarrytown, NY: Regeneron Pharmaceuticals, Inc.; 2022.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13814
-
Product Reviews
