What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Edarbi (Azilsartan Medoxomil)
Prescription Required
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Product Details
Description
Your doctor may prescribe Edarbi if you have high blood pressure, which is also called hypertension.
Hypertension is a chronic condition where high blood pressure can slowly damage the various organs of the body. Edarbi is an angiotensin II receptor blocker that lowers blood pressure to treat hypertension.
Angiotensin II is a protein in the blood that increases blood pressure. Edarbi blocks this protein to keep blood pressure low.
Fact Table
Formula
C25H20N4O5
License
US FDA
Bioavailability
60%
Legal status
Rx Only
Chemical Name
Azilsartan
Elimination half-life
11 hrs
Dosage (Strength)
40mg, 80mg
Pregnancy
Consult Doctor
Brands
Edarbi, Azilva
Protein binding
99%
PubChem CID
135415867
MedlinePlus
a611028
ChEBI
68850
ATC code
C09CA09
DrugBank
DB08822
KEGG
D08864
Routes of administration
By mouth
Directions
Take Edarbi exactly as prescribed by your doctor. The starting dose of Edarbi is 40 mg by mouth once daily with or without food. The dose may be increased to 80 mg once daily if needed. Take Edarbi at the same time each day.
Ingredients
The active ingredient in Edarbi generic is azilsartan.
Interactions
There are many potential interactions with Edarbi and other medications, including prescription, over-the-counter (OTC), and herbal supplements. Some interactions may include:
- Alfuzosin
- Aliskiren
- Amifostine
- Amphetamines
- Barbiturates
- Benazepril
- Bromperidol
- Captopril
- CycloSPORINE
- Dexmethylphenidate
- Drospirenone
- Duloxetine
- Enalapril
- Eplerenone
- Heparin
- Levodopa-Containing Products
- Lisinopril
- Lithium
- Methylphenidate
- Nitroprusside
- Nonsteroidal Anti-Inflammatory Agents
- Obinutuzumab
- Prostacyclin Analogues
- Quinapril
- Ranolazine
- Sildenafil
- Sodium Phosphates
- Tacrolimus
- Tadalafil
- Trimethoprim
- Vardenafil
Tell your doctor and pharmacist about all medications you are taking before starting Edarbi.
Cautions
Edarbi can increase the risk of high potassium levels. Your doctor will monitor your potassium while you take this medication.
Tell your doctor if you have a history of angioedema, or swelling under the skin, before starting this drug. Edarbi can worsen angioedema in some people.
Side Effects
Common Edarbi side effects can include:
- Angioedema
- Asthenia
- Cough
- Decreased hemoglobin
- Decreased red blood cells
- Decreased hematocrit
- Diarrhea
- Dizziness
- Fatigue
- Hypotension
- Increased serum creatinine
- Leukocytosis
- Muscle spasm
- Nausea
- Orthostatic dizziness
- Orthostatic hypotension
- Pruritus
- Skin rash
- Thrombocytopenia
References
- Edarbi [package insert]. Deerfield, IL: Takeda; 2011.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12297
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