What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Edarbi (Azilsartan Medoxomil)
Prescription Required
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Product Details
Description
Your doctor may prescribe Edarbi if you have high blood pressure, which is also called hypertension.
Hypertension is a chronic condition where high blood pressure can slowly damage the various organs of the body. Edarbi is an angiotensin II receptor blocker that lowers blood pressure to treat hypertension.
Angiotensin II is a protein in the blood that increases blood pressure. Edarbi blocks this protein to keep blood pressure low.
Fact Table
Formula
C25H20N4O5
License
US FDA
Bioavailability
60%
Legal status
Rx Only
Chemical Name
Azilsartan
Elimination half-life
11 hrs
Dosage (Strength)
40mg, 80mg
Pregnancy
Consult Doctor
Brands
Edarbi, Azilva
Protein binding
99%
PubChem CID
135415867
MedlinePlus
a611028
ChEBI
68850
ATC code
C09CA09
DrugBank
DB08822
KEGG
D08864
Routes of administration
By mouth
Directions
Take Edarbi exactly as prescribed by your doctor. The starting dose of Edarbi is 40 mg by mouth once daily with or without food. The dose may be increased to 80 mg once daily if needed. Take Edarbi at the same time each day.
Ingredients
The active ingredient in Edarbi generic is azilsartan.
Interactions
There are many potential interactions with Edarbi and other medications, including prescription, over-the-counter (OTC), and herbal supplements. Some interactions may include:
- Alfuzosin
- Aliskiren
- Amifostine
- Amphetamines
- Barbiturates
- Benazepril
- Bromperidol
- Captopril
- CycloSPORINE
- Dexmethylphenidate
- Drospirenone
- Duloxetine
- Enalapril
- Eplerenone
- Heparin
- Levodopa-Containing Products
- Lisinopril
- Lithium
- Methylphenidate
- Nitroprusside
- Nonsteroidal Anti-Inflammatory Agents
- Obinutuzumab
- Prostacyclin Analogues
- Quinapril
- Ranolazine
- Sildenafil
- Sodium Phosphates
- Tacrolimus
- Tadalafil
- Trimethoprim
- Vardenafil
Tell your doctor and pharmacist about all medications you are taking before starting Edarbi.
Cautions
Edarbi can increase the risk of high potassium levels. Your doctor will monitor your potassium while you take this medication.
Tell your doctor if you have a history of angioedema, or swelling under the skin, before starting this drug. Edarbi can worsen angioedema in some people.
Side Effects
Common Edarbi side effects can include:
- Angioedema
- Asthenia
- Cough
- Decreased hemoglobin
- Decreased red blood cells
- Decreased hematocrit
- Diarrhea
- Dizziness
- Fatigue
- Hypotension
- Increased serum creatinine
- Leukocytosis
- Muscle spasm
- Nausea
- Orthostatic dizziness
- Orthostatic hypotension
- Pruritus
- Skin rash
- Thrombocytopenia
References
- Edarbi [package insert]. Deerfield, IL: Takeda; 2011.
Frequently Asked Questions about Edarbi (Azilsartan Medoxomil)
What is Edarbi (Azilsartan Medoxomil)?
Edarbi is a prescription medication that contains the active ingredient Azilsartan Medoxomil. It belongs to a class of drugs known as angiotensin II receptor blockers (ARBs) and is used to treat high blood pressure (hypertension).
How does Edarbi work to lower blood pressure?
Edarbi works by relaxing blood vessels, which helps to lower blood pressure. It does this by blocking the effects of a hormone called angiotensin II, which can narrow blood vessels and raise blood pressure.
What conditions is Edarbi used to treat?
Edarbi is primarily prescribed to treat hypertension (high blood pressure) in adults. Controlling high blood pressure can help reduce the risk of heart attacks, strokes, and other cardiovascular problems.
Is Edarbi available over the counter (OTC)?
No, Edarbi is not available over the counter. It is a prescription medication, so you'll need a doctor's prescription to obtain it.
How should I take Edarbi?
Follow your doctor's instructions carefully. Typically, Edarbi is taken once daily with or without food. It's important to take it at the same time each day to maintain consistent blood pressure control.
What are the potential side effects of Edarbi?
Like all medications, Edarbi may have side effects. Common side effects can include dizziness, diarrhea, and headache. Serious side effects are rare but may include allergic reactions and kidney problems. Contact your doctor if you experience any concerning side effects.
Can I use Edarbi if I have other medical conditions or take other medications?
Inform your healthcare provider about all your medical conditions and medications you are taking, as they may affect the suitability of Edarbi for you. Your doctor will consider your medical history to determine if Edarbi is safe and appropriate.
How long will I need to take Edarbi?
The duration of Edarbi treatment will be determined by your healthcare provider based on your individual health and blood pressure control. It may be a long-term medication to manage hypertension effectively.
Can Edarbi be used during pregnancy or while breastfeeding?
If you are pregnant, planning to become pregnant, or breastfeeding, discuss the use of Edarbi with your healthcare provider. It's important to weigh the potential risks and benefits in these situations.
What should I do if I miss a dose of Edarbi?
If you miss a dose, take it as soon as you remember. However, if it's close to the time for your next scheduled dose, skip the missed dose and continue with your regular dosing schedule. Do not take two doses at the same time.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 12297
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