What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Evotaz (Atazanavir / Cobicistat)
Prescription Required
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Product Details
Description
For people with Acquired Immunodeficiency Syndrome (AIDS), the disease is chronic and life-changing. A doctor may prescribe Evotaz to prevent further development of AIDS and progression of symptoms.
AIDS is caused by Human Immunodeficiency Virus (HIV-1), which is currently incurable. However, medications like Evotaz prevent the replication of viral particles, slowing the infection.
Directions
The dosage of Evotaz is one tablet by mouth once daily. Do not change your dosage without speaking to your doctor.
Ingredients
Evotaz has two active ingredients: atazanavir 300 mg and cobicistat 150 mg.
Atazanavir blocks a critical protein in HIV viral particles and prevents it from replicating. Cobicistat "boosts" the amount of atazanavir in the bloodstream by slowing its metabolism.
Interactions
Many drug interactions exist with Evotaz. Do not start any new medications without telling the doctor that prescribed Atazanavir. Common interactions include:
- Alfuzosin
- Alprazopam
- Aprepitant
- Avanafil
- Bosutinib
- Budesonide
- Buprenorphine
- Carbamazepine
- Cisapride
- Conivaptan
- Dapoxetine
- Domperidone
- Dronedarone
- Elbasvir and Grazoprevir
- Eplerenone
- Ergot Derivatives
- Everolimus
- Fluticasone
- Fosaprepitant
- Fusidic Acid
- Ibrutinib
- Irinotecan Products
- Ivabradine
- Lurasidone
- Midazolam
- Ombitasvir, Paritaprevir, and Ritonavir
- Paclitaxel
- Phenobarbital
- Pimozide
- Primidone
- Ranolazine
- Regorafenib
- Repaglinide
- Rifampin
- Ritonavir
- Rivaroxaban
- Salmeterol
- Saquinavir
- Simeprevir
- Simvastatin
- St John's Wort
- Suvorexant
- Tamsulosin
- Ticagrelor
- Triazolam
- Vincristine
Cautions
Evotaz can cause the redistribution of fat tissue. Tell your healthcare provider if you experience this symptom.
Use caution if you have a history of kidney or liver problems.
Use caution if you have a history of bleeding disorders or diabetes.
Side Effects
Tell your doctor and pharmacist if you experience any of the following Evotaz side effects:
- Abnormal dreams
- Decreased neutrophils
- Depression
- Diarrhea
- Dyslipidemia
- Fanconi syndrome
- Fatigue
- Glycosuria
- Headache
- Hematuria
- Increased bilirubin
- Increased creatinine phosphokinase
- Increased gamma-glutamyl transferase
- Increased serum glucose
- Insomnia
- Jaundice
- Nausea
- Renal disease
- Skin rash
- Upper abdominal pain
- Vomiting
References
- Evotaz [package insert]. Princeton, NJ: Bristol-Myers Squibb; 2020.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 13223
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