Description
Firvanq (vancomycin hydrochloride for oral solution) is an antibacterial used for the treatment of Clostridium difficile-associated diarrhea and enterocolitis caused by Staphylococcus aureus (including methicillin-resistant strains) in adults and pediatric patients.
Fact Table |
Formula |
C66H76Cl3N9O24 |
License |
US FDA, EU EMA |
Bioavailability |
less than 10% |
Legal status |
Rx-Only |
Chemical Name |
Vancomycin HCL |
Elimination half-life |
4 to 6 hours |
Dosage (Strength) |
25 mg/ml, 50 mg/ml |
Pregnancy |
not recommended |
Brands |
Firvanq |
Protein binding |
55% |
PubChem CID |
6420023 |
MedlinePlus |
a604038 |
ChEBI |
9932 |
ATC code |
J01XA01 |
DrugBank |
DB00512 |
KEGG |
D00926 |
Routes of administration |
Oral |
Directions
Each kit of Firvanq consists of vancomycin hydrochloride USP, powder for oral solution, equivalent to 3.75 grams or 7.5 grams or 15.0 grams vancomycin, and grape-flavored diluent.
Clostridium difficile-associated diarrhea:
- Adults (18 years and older): 125 mg by mouth four times daily for 10 days
- Pediatrics (less than 18 years old): 40 mg per kg by mouth in 3 or 4 divided doses for 7 to 10 days. Do not exceed 2,000 mg daily.
Enterocolitis caused by Staphylococcus aureus:
- Adults (18 years and older): 500 mg to 2,000 mg by mouth in 3 or 4 divided doses for 7 to 10 days.
- Pediatrics (less than 18 years old): 40 mg per kg by mouth in 3 or 4 divided doses for 7 to 10 days. Do not exceed 2,000 mg daily.
Shake Firvanq oral solution well before each dose. Use a measuring device to measure out the appropriate dose (in milliliters). Store Firvanq in the refrigerator. Discard Firvanq after 14 days or if it looks cloudy or has particulates.
Ingredients
The active ingredient in Firvanq is Vancomycin Hydrochloride.
Contraindications
Discuss your allergies with your doctor. Do not take Firvanq if you are allergic to vancomycin or any of the other ingredients in Firvanq.
Cautions
- Discuss all your medications with your doctor, including all prescription, over-the-counter, vitamins, and herbal supplements.
- Serum levels of vancomycin may increase while taking Firvanq. Serum levels may be monitored.
- Firvanq can cause kidney damage. Kidney function should be monitored.
- Firvanq may cause hearing problems.
- Firvanq may cause severe skin reactions such as rashes, lesions, or blisters.
- Tell your doctor if you are pregnant or plan to become pregnant.
- Tell your doctor if you are breastfeeding or plan to breastfeed.
Side Effects
The most common side effects associated with Firvanq include nausea, upset stomach, and low potassium levels. These are not all the possible side effects. Tell your doctor right away if you develop side effects that are bothersome or won't go away.
Reference:
Firvanq Prescribing Information. Wilmington, MA: azurity pharmaceuticals.
About Dr. Savannah Muncy (Page Author)
Dr. Muncy (PharmD) studied science and education as an undergraduate before attending the Appalachian College of Pharmacy where she completed her PharmD in three years. She is currently using her pharmacy and healthcare expertise to write medical content for clients all around the world. She is focused on delivering the most current, accurate, and engaging information to healthcare professionals and patients. Read More....
IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Product Code : 13580