What is a Generic Drug?
A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Frova (Frovatriptan)
Also Known as Migrex
Prescription Required
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Product Details
Description
Frova (frovatriptan succinate) is used to treat migraines in adults.
Frova should not be used until you have been diagnosed with a migraine.
Frova should not be used to prevent migraines.
Frova should not be used to treat cluster headaches.
Fact Table
Formula
C14H17N3O
License
US FDA
Bioavailability
20–30%
Legal status
Rx-Only
Chemical Name
Frovatriptan
Elimination half-life
26 hours
Dosage (Strength)
2.5mg
Pregnancy
No Known Risks
Brands
Frova
Protein binding
60%
PubChem CID
77992
MedlinePlus
a604013
ChEBI
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ATC code
N02CC07
DrugBank
DB00998
KEGG
D07997
Routes of administration
Oral
Directions
Frova is available in 2.5 mg oral tablets.
Follow the directions that are on the label of your prescription. Carefully read all the information that comes with your prescription. Talk to your doctor or pharmacist about any concerns and ask them any questions you may have.
One tablet should be taken by mouth with fluids. If your migraine does not go away, you may take another tablet 2 hours after the first dose. Do not take more than 3 tablets per 24 hours.
Ingredients
Each Frova tablet contains frovatriptan succinate, a serotonin (5HT1B/1D) receptor agonist. Other ingredients include lactose NF, microcrystalline cellulose NF, colloidal silicon dioxide NF, sodium starch glycolate NF, magnesium stearate NF, hypromellose USP, polyethylene glycol 3000 USP, triacetin USP, and titanium dioxide USP.
Contraindications
Frova should not be taken by patients if they:
- Have ever had coronary artery disease or coronary artery vasospasm
- Have Wolff-Parkinson-White syndrome or arrhythmias caused by other cardiac accessory conduction pathway problems
- Have ever had a stroke, transient ischemic attack, or hemiplegic or basilar migraine
- Have peripheral vascular disease
- Have ischemic bowel disease
- Have high blood pressure that is not controlled
- Have taken another 5-HT1 agonist or an ergotamine-containing or ergot-type medication within the past 24 hours.
- Are allergic to frovatriptan or any of its other ingredients or excipients.
Cautions
- Before starting treatment with Frova, you should inform your doctor of:
- All the medications you take, including prescription, nonprescription, vitamins, and herbal supplements
- Your allergies
- Your medical history and current medical conditions
- Your pregnancy or breastfeeding status
- Heart attack or other cardiac events can occur after taking Frova.
- Frova can cause heart arrhythmias that can be life-threatening.
- Pain, tightness, pressure, and heaviness in the chest, throat, neck, and jaw can occur after taking Frova. These effects are generally not related to the heart. However, you should talk to your doctor about your risks for cardiac events.
- Cerebral bleeding, subarachnoid bleeding, stroke, or other cerebrovascular events that can be life-threatening can occur in patients treated with Frova.
- Frova can cause non-coronary vasospastic events like peripheral vascular ischemia, gastrointestinal vascular ischemia and infarction (causing stomach pain and bloody diarrhea), splenic infarction, and Raynaud's syndrome. Blindness that may be permanent or partial vision loss can also occur.
- Taking too much Frova can cause or worsen headaches.
- Frova can cause serotonin syndrome, especially if taken with other medications that can cause serotonin syndrome. Seek medical care right away if you develop agitation, hallucinations, rapid heart rate, unstable blood pressure, coordination problems, overactive reflexes, nausea, vomiting, or diarrhea.
- Frova can cause serious elevations in blood pressure.
- Frova can cause serious allergic reactions. Seek emergency care right away if you develop trouble breathing, swelling of your face, lips, tongue, or throat, a rash, or fast heart rate.
Side Effects
Like with any medication, Frova medication can cause side effects. The most common are dizziness, headache, tingling or prickling sensation, dry mouth, indigestion, hot or cold sensation, chest pain, skeletal pain, and flushing. Call your doctor if you have side effects that bother you or won't disappear.
Reference:
Frova- frovatriptan succinate tablet, film coated. Malvern, PA: Endo Pharmaceuticals, Inc.; 2018.
IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.Product Code : 6438
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