What is a Generic Drug?

A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.

The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.

Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.

Gabitril (Tiagabinet)

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Brand

Gabitril (Tiagabinet)

Prescription Required

Strength
Qty
5mg
10mg

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  • Product Details

    Description

    Gabitril is a medication prescribed to treat focal seizure disorders.

    Focal seizures are seizures that start in one part of the brain and spread to other regions. Some people experience "fully aware focal seizures" and are still conscious and aware of having a seizure while it's happening (simple partial seizure). Others may lose consciousness or not be aware of the seizure, called a complex partial seizure.

    Symptoms may include muscle contractions, eye movements, stomach pain, numbness, or contractions on one side of the body.

    Gabitril works by enhancing the activity of the neurotransmitter gamma-aminobutyric acid (GABA). GABA suppresses signals in nerve cells, including the type of signals that cause seizures.

    Fact Table

    Formula

    C20H25NO2S2

    License

    US FDA

    Bioavailability

    90–95%

    Legal status

    Rx only

    Chemical Name

    Tiagabine

    Elimination half-life

    5–8 hours

    Dosage (Strength)

    5mg,10mg

    Pregnancy

    Consult Doctor

    Brands

    Gabitril

    Protein binding

    96%

    PubChem CID

    60648

    MedlinePlus

    a698014

    ChEBI

    9586

    ATC code

    N03AG06

    DrugBank

    DB00906

    KEGG

    D08588

    Routes of administration

    Oral (tablets)

    Directions

    Take Gabitril exactly as directed by your doctor. 

    The starting Gabitril dosage is typically 4 mg by mouth once daily. Your doctor may increase the dosage by 4-8 mg each week. The maximum daily dosage is 56 mg divided two to four times throughout the day.

    Ingredients

    The active ingredient in Gabitril is tiagabine.

    Interactions

    Tell your doctor if you are taking any of the following:

    • Alcohol 
    • Apalutamide
    • Azelastine 
    • Brimonidine 
    • Bromperidol
    • Buprenorphine
    • Cannabinoid-Containing Products
    • Carbamazepine
    • Chlormethiazole
    • CNS Depressants
    • Codeine
    • Doxylamine
    • Enzalutamide
    • Erdafitinib
    • Fentanyl
    • Flunitrazepam
    • Fosphenytoin
    • Hydrocodone
    • Hydromorphone
    • Hydroxyzine
    • Kava kava
    • Lumacaftor
    • Lumacaftor-ivacaftor
    • Magnesium Sulfate
    • Mefloquine
    • Metoclopramide
    • Mitotane
    • Morphine
    • Orlistat
    • Orphenadrine
    • Oxomemazine
    • Oxycodone
    • Oxymorphone
    • Phenobarbital
    • Phenytoin
    • Primidone
    • Rifampin (rifampicin)
    • Suvorexant
    • Thalidomide
    • Tocilizumab


    The above medications have the potential to interact with Gabitril. 

    Cautions

    Gabitril can cause CNS depression, so use caution if you are mixing with other CNS depressants.

    Do not stop Gabitril without talking with your doctor. Doing so can increase the risk of seizures.

    Ask your doctor or pharmacist for a complete list of precautions that apply to you.

    Side Effects

    Common adverse reactions to Gabitril medication may include:

    • Accidental injury
    • Dizziness
    • Drowsiness
    • Infection
    • Lack of concentration
    • Nausea
    • Nervousness
    • Tremor
    • Weakness

    References

    1. Gabitril [package insert]. Frazer, PA: Cephalon; 2009.

    Dr Conor Sheehy
    About Dr. Conor Sheehy (Page Author)

    Dr. Sheehy (BSc Molecular Biology, PharmD) works a clinical pharmacist specializing in cardiology, oncology, and ambulatory care. He’s a board-certified pharmacotherapy specialist (BCPS), and his experience working one-on-one with patients to fine tune their medication and therapy plans for optimal results makes him a valuable subject matter expert for our pharmacy. Read More....


    IMPORTANT NOTE: The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.

    Product Code : 5481

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