A generic drug is a copy of the brand-name drug with the same dosage, safety, strength, quality, consumption method, performance, and intended use. Before generics become available on the market, the generic company must prove it has the same active ingredients as the brand-name drug and works in the same way and in the same amount of time in the body.
The only differences between generics and their brand-name counterparts is that generics are less expensive and may look slightly different (eg. different shape or color), as trademarks laws prevent a generic from looking exactly like the brand-name drug.
Generics are less expensive because generic manufacturers don't have to invest large sums of money to develop a drug. When the brand-name patent expires, generic companies can manufacture a copy of the brand-name and sell it at a substantial discount.
Gleostine (Lomustine)
Brand
Gleostine (Lomustine)
Prescription Required
Strength
Pack Size
10mg
40mg
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GLEOSTINE (lomustine) is prescribed to treat certain types of cancers. It is a chemotherapy agent, and should only be used under the close supervision of a physician.
GLEOSTINE can be prescribed for the following types of cancers:
Brain tumors; primary and metastatic tumors.
Hodgkin’s lymphoma, following disease progression with initial chemotherapy.
GLEOSTINE attaches to DNA and RNA, preventing the replication of cancerous cells. GLEOSTINE also attaches to specific proteins, making them inactive.
Directions
The normal dose of GLEOSTINE is 130 mg per meter-squared, rounded to the nearest 5 mg.
GLEOSTINE is available in the following capsule sizes:
5 mg
10 mg
40 mg
100 mg
One single dose of GLEOSTINE is administered every six weeks.
Ingredients
The active ingredient in GLEOSTINE is lomustine.
Interactions
Speak with your healthcare provider if you are taking any of the following:
Baracitinib
BCG (Bacillus Calmette-Guerin)
Chloramphenicol
Cladribine
Clozapine
Coccidiodes immitis Skin Test
Deferiprone
Denosumab
Dipyrone
Echinacea
Fingolimod
Inebilizumab
Leflunomide
Lenograstim
Lipegfilgrastim
Mesalamine
Natalizumab
Nivolumab
Ocrelizumab
Ozanimod
Palifermin
Pidotimod
Pimecrolimus
Promazine
Roflumilast
Siponimod
Sipuleucel-T
Tacrolimus
Tertomotide
Tofacitinib
Trastuzumab
Upadacitinib
Vaccines
Cautions
An overdose of GLEOSTINE can be fatal. Take GLEOSTINE exactly as directly once every six weeks.
GLEOSTINE can cause myelosuppression (bone marrow suppression), which is a decrease in the activity of bone marrow cells. Complete blood counts need to be monitored regularly while taking GLEOSTINE.
GLEOSTINE should not be used by women who are pregnant or breastfeeding.
GLEOSTINE can cause lung toxicity. Lung function should be monitored while taking this medication.
Long-term use can cause secondary malignancies.
Monitor liver function and kidney function while taking GLEOSTINE.
Side Effects
Common adverse reactions to GLEOSTINE may include:
Alopecia
Ataxia
Blindness
Disorientation
Dysarthria
Lethargy
Nausea
Optic atrophy
Stomatitis
Visual disturbances
Vomiting
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IMPORTANT NOTE:
The above information is intended to increase awareness of health information and does not suggest treatment or diagnosis. This information is not a substitute for individual medical attention and should not be construed to indicate that use of the drug is safe, appropriate, or effective for you. See your health care professional for medical advice and treatment.
Prescription Required
